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Cellosaurus Raji (CVCL_0511)

[Text version]
Cell line name Raji
Synonyms RAJI; P1-Raji; GM04671
Accession CVCL_0511
Resource Identification Initiative To cite this cell line use: Raji (RRID:CVCL_0511)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: ENCODE project common cell types; tier 3.
Part of: LL-100 blood cancer cell line panel.
Part of: MD Anderson Cell Lines Project.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Population: African; Nigerian.
Characteristics: Genetically heterogeneous, consists of 2 subclones (PubMed=27566572).
Virology: Contains 50-60 integrated copies of the EBV genome. One copy is integrated in intron 1 of the BACH2 gene (PubMed=14982850).
Doubling time: 23.2 hours (PubMed=8847894); ~24-36 hours (DSMZ=ACC-319); ~20 hours (HIVReagentProgram=ARP-9944).
Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526; Sanger).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Omics: Virome analysis using RNAseq.
Misspelling: BAJI; Cosmic=998718.
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Sequence variations
HLA typing Source: PubMed=25960936
Class I
HLA-AA*03:01,03:01
HLA-BB*15:10,15:10
HLA-CC*04:01,03:04
Class II
HLA-DQDQA1*05:01,01:01
DQB1*05:01,02:01
HLA-DRDRB1*10:01,03:01

Source: IPD-IMGT/HLA=11295
Class I
HLA-AA*03:01:01:01
HLA-BB*15:10,15:CXU
HLA-CC*03:04:02,04:01:01:01
Class II
HLA-DPDPB1*01:01:01
HLA-DQDQA1*01:01:01,05:01:01:01
DQB1*02:01:01,05:01:01
HLA-DRDRA*01:01:01:01
DRB1*03:01:01:01,10:01:01:01
DRB3*02

Source: CLS=300359
Class I
HLA-AA*03:01:01
HLA-BB*15:10:01
HLA-CC*03:04:02,04:01:01
Class II
HLA-DPDPB1*01:01:01
HLA-DQDQA1*01:05:01,05:01:01
DQB1*02:01:01,05:01:01
HLA-DRDRB1*03:01:01,10:01:01

Source: DSMZCellDive=ACC-319
Class I
HLA-AA*03:01:01,03:01:01
HLA-BB*15:10:01,15:10:01
HLA-CC*03:04:02,04:01:01
Class II
HLA-DPDPA1*02:02:02,02:02:02
DPB1*01:01:01,01:01:01
HLA-DQDQA1*01:05:01,05:01:01
DQB1*02:01:01,05:01:01
HLA-DRDRA*01:01:01,01:01:01
DRB1*03:01:01,10:01:01
Genome ancestry Source: PubMed=30894373

Origin% genome
African99.39
Native American0
East Asian, North0.6
East Asian, South0
South Asian0
European, North0
European, South0
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B7VS (Abcam Raji AATF KO)CVCL_B7VT (Abcam Raji ABCB1 KO)CVCL_D2HQ (Abcam Raji ABI1 KO)
CVCL_D2HR (Abcam Raji ACAA1 KO)CVCL_D2HS (Abcam Raji ACOT13 KO)CVCL_D2HT (Abcam Raji ACTR3 KO)
CVCL_D2HU (Abcam Raji ACVR2B KO)CVCL_D2HV (Abcam Raji ACVRL1 KO)CVCL_D2HW (Abcam Raji ACY1 KO)
CVCL_D2HX (Abcam Raji ADD1 KO)CVCL_B7VU (Abcam Raji AGTR1 KO)CVCL_D2HY (Abcam Raji AHCY KO)
CVCL_B7VV (Abcam Raji AHR KO)CVCL_B7VW (Abcam Raji AIM2 KO)CVCL_D2HZ (Abcam Raji AKR7A2 KO)
CVCL_D2I0 (Abcam Raji ALAD KO)CVCL_B7VX (Abcam Raji ALCAM KO)CVCL_D2I1 (Abcam Raji ALDH1A2 KO)
CVCL_D2I2 (Abcam Raji ALDH4A1 KO)CVCL_D2I3 (Abcam Raji ALDOB KO)CVCL_B7VY (Abcam Raji ALKBH1 KO)
CVCL_D2I4 (Abcam Raji ALOX5AP KO)CVCL_B7VZ (Abcam Raji ALYREF KO)CVCL_B7W0 (Abcam Raji APOBEC3B KO)
CVCL_D2I5 (Abcam Raji ARSA KO)CVCL_B7W1 (Abcam Raji ASAH1 KO)CVCL_D2I6 (Abcam Raji ASL KO)
CVCL_B7W2 (Abcam Raji ATF5 KO)CVCL_B7W3 (Abcam Raji ATG3 KO)CVCL_B7W4 (Abcam Raji ATG9A KO)
CVCL_D2I7 (Abcam Raji ATXN2 KO)CVCL_B7W5 (Abcam Raji BAK1 KO)CVCL_D2I8 (Abcam Raji BAZ2A KO)
CVCL_D2I9 (Abcam Raji BCAT1 KO)CVCL_D2IA (Abcam Raji BCAT2 KO)CVCL_B7W6 (Abcam Raji BMPR2 KO)
CVCL_B7W7 (Abcam Raji BRD1 KO)CVCL_B7W8 (Abcam Raji BRD2 KO)CVCL_B7W9 (Abcam Raji BRD9 KO)
CVCL_D2IB (Abcam Raji BRMS1 KO)CVCL_B7WA (Abcam Raji BTG1 KO)CVCL_B7WB (Abcam Raji BTK KO)
CVCL_D2IC (Abcam Raji BTLA KO)CVCL_B7WC (Abcam Raji BTRC KO)CVCL_B7WD (Abcam Raji C3 KO)
CVCL_D2ID (Abcam Raji CA8 KO)CVCL_D2IE (Abcam Raji CALU KO)CVCL_D2IF (Abcam Raji CAMK4 KO)
CVCL_D2IG (Abcam Raji CASP2 KO)CVCL_B7WE (Abcam Raji CASP3 KO)CVCL_D2IH (Abcam Raji CBLC KO)
CVCL_B7WG (Abcam Raji CCL22 KO)CVCL_B7WF (Abcam Raji CCRL2 KO)CVCL_D2II (Abcam Raji CCS KO)
CVCL_B1BK (Abcam Raji CD27 KO)CVCL_B7WH (Abcam Raji CD36 KO)CVCL_B7WI (Abcam Raji CD48 KO)
CVCL_B7WJ (Abcam Raji CD58 KO)CVCL_B7WK (Abcam Raji CD59 KO)CVCL_B1BL (Abcam Raji CD74 KO 1)
CVCL_B1BM (Abcam Raji CD74 KO 2)CVCL_B8AM (Abcam Raji CD79A KO)CVCL_B1BN (Abcam Raji CD80 KO)
CVCL_B7WL (Abcam Raji CD81 KO)CVCL_B7WM (Abcam Raji CD83 KO)CVCL_B1BP (Abcam Raji CD86 KO)
CVCL_D2IJ (Abcam Raji CHP1 KO)CVCL_B7WN (Abcam Raji CITED2 KO)CVCL_D2IK (Abcam Raji CLASP1 KO)
CVCL_D2IL (Abcam Raji CLPP KO)CVCL_B7WP (Abcam Raji CLU KO)CVCL_D2IM (Abcam Raji CMAS KO)
CVCL_B7WQ (Abcam Raji CMKLR1 KO)CVCL_B7WR (Abcam Raji CMTM6 KO)CVCL_D2IN (Abcam Raji CNDP2 KO)
CVCL_B7WS (Abcam Raji CNR2 KO)CVCL_D2IP (Abcam Raji CRYZ KO)CVCL_B7WT (Abcam Raji CST3 KO)
CVCL_B7WU (Abcam Raji CTSB KO)CVCL_B7WV (Abcam Raji CUL2 KO)CVCL_B7WW (Abcam Raji CUL3 KO)
CVCL_B7WX (Abcam Raji CUL4B KO)CVCL_B1BQ (Abcam Raji CXCR5 KO)CVCL_B7WY (Abcam Raji CXXC1 KO)
CVCL_D2IQ (Abcam Raji CYB5A KO)CVCL_D2IR (Abcam Raji CYB5R3 KO)CVCL_B7WZ (Abcam Raji DCP2 KO)
CVCL_D2IS (Abcam Raji DFFB KO)CVCL_D2IT (Abcam Raji DGAT1 KO)CVCL_D2IU (Abcam Raji DGKA KO)
CVCL_B7X0 (Abcam Raji DLL1 KO)CVCL_D2IV (Abcam Raji DNPEP KO)CVCL_D2IW (Abcam Raji DNTT KO)
CVCL_D2IX (Abcam Raji DPP8 KO)CVCL_B7X1 (Abcam Raji DVL3 KO)CVCL_B7X2 (Abcam Raji EGLN1 KO)
CVCL_B7X3 (Abcam Raji EHMT2 KO)CVCL_B7X4 (Abcam Raji EIF2AK4 KO)CVCL_B7X5 (Abcam Raji EPHB4 KO)
CVCL_D2IY (Abcam Raji EPHX1 KO)CVCL_D2IZ (Abcam Raji EPHX2 KO)CVCL_D2J0 (Abcam Raji EPN1 KO)
CVCL_B7X6 (Abcam Raji ERAP1 KO)CVCL_B7X7 (Abcam Raji ETS2 KO)CVCL_D2J1 (Abcam Raji ETV4 KO)
CVCL_B7X8 (Abcam Raji EXO1 KO)CVCL_B7X9 (Abcam Raji FABP4 KO)CVCL_D2J2 (Abcam Raji FDX1 KO)
CVCL_D2J3 (Abcam Raji FECH KO)CVCL_B7XA (Abcam Raji FKBP5 KO)CVCL_D2J4 (Abcam Raji FOLR2 KO)
CVCL_D2J5 (Abcam Raji FOSB KO)CVCL_B7XB (Abcam Raji FOXO1 KO)CVCL_B7XC (Abcam Raji FOXO3 KO)
CVCL_D2J6 (Abcam Raji FPGS KO)CVCL_D2J7 (Abcam Raji FRK KO)CVCL_B7XD (Abcam Raji FST KO)
CVCL_B7XE (Abcam Raji FTL KO)CVCL_D2J8 (Abcam Raji FUBP1 KO)CVCL_B7XF (Abcam Raji FZD7 KO)
CVCL_B7XG (Abcam Raji GAB1 KO)CVCL_D2J9 (Abcam Raji GAMT KO)CVCL_D2JA (Abcam Raji GANAB KO)
CVCL_D2JB (Abcam Raji GART KO)CVCL_D2JC (Abcam Raji GCDH KO)CVCL_D2JD (Abcam Raji GGH KO)
CVCL_B7XH (Abcam Raji GLB1 KO)CVCL_D2JE (Abcam Raji GLG1 KO)CVCL_D2JF (Abcam Raji GLUL KO)
CVCL_D2JG (Abcam Raji GNE KO)CVCL_B7XI (Abcam Raji GPR132 KO)CVCL_D2JH (Abcam Raji GRK3 KO)
CVCL_D2JI (Abcam Raji GRK6 KO)CVCL_D2JJ (Abcam Raji GUSB KO)CVCL_B7XJ (Abcam Raji GZMA KO)
CVCL_D2JK (Abcam Raji HDAC10 KO)CVCL_D2JL (Abcam Raji HDGF KO)CVCL_D2JM (Abcam Raji HEXA KO)
CVCL_D2JN (Abcam Raji HIF1AN KO)CVCL_B7XK (Abcam Raji HLA-B KO)CVCL_D2JP (Abcam Raji HMBS KO)
CVCL_D2JQ (Abcam Raji HMGCS2 KO)CVCL_D2JR (Abcam Raji HMOX2 KO)CVCL_B7XL (Abcam Raji HNF1B KO)
CVCL_D2JS (Abcam Raji HSD17B10 KO)CVCL_D2JT (Abcam Raji HSD17B4 KO)CVCL_D2JU (Abcam Raji HSPA13 KO)
CVCL_D2JV (Abcam Raji HSPA1L KO)CVCL_D2JW (Abcam Raji HSPA2 KO)CVCL_D2JX (Abcam Raji HSPA4 KO)
CVCL_B7XM (Abcam Raji HSPG2 KO)CVCL_D2JY (Abcam Raji HSPH1 KO)CVCL_B7XN (Abcam Raji ID2 KO)
CVCL_D2JZ (Abcam Raji IKZF3 KO)CVCL_D2K0 (Abcam Raji IL13RA1 KO)CVCL_B7XP (Abcam Raji IL17RB KO)
CVCL_D2K1 (Abcam Raji IL2RG KO)CVCL_D2K2 (Abcam Raji IMPDH1 KO)CVCL_D2K3 (Abcam Raji ITGA4 KO)
CVCL_B7XQ (Abcam Raji ITPR3 KO)CVCL_B7XR (Abcam Raji JAG1 KO)CVCL_B7XS (Abcam Raji JMJD6 KO)
CVCL_B7XT (Abcam Raji KAT7 KO)CVCL_B7XU (Abcam Raji KDM1B KO)CVCL_B7XV (Abcam Raji KDM6B KO)
CVCL_B7XW (Abcam Raji KPNA2 KO)CVCL_B7XX (Abcam Raji LAIR1 KO)CVCL_B7XY (Abcam Raji LAMP2 KO)
CVCL_B7XZ (Abcam Raji LDHA KO)CVCL_D2K4 (Abcam Raji LGALS8 KO)CVCL_B7Y0 (Abcam Raji LGR6 KO)
CVCL_D2K5 (Abcam Raji LIAS KO)CVCL_B7Y1 (Abcam Raji LMNB1 KO)CVCL_D2K6 (Abcam Raji LPXN KO)
CVCL_B7Y2 (Abcam Raji MACROH2A1 KO)CVCL_D2K7 (Abcam Raji MAEA KO)CVCL_B7Y3 (Abcam Raji MAGEA3 KO)
CVCL_B7Y4 (Abcam Raji MAP2K3 KO)CVCL_B7Y5 (Abcam Raji MAP3K3 KO)CVCL_D2K8 (Abcam Raji MAP3K4 KO)
CVCL_D2K9 (Abcam Raji MAP4K1 KO)CVCL_D2KA (Abcam Raji MAP4K4 KO)CVCL_B7Y6 (Abcam Raji MAPK7 KO)
CVCL_D2KB (Abcam Raji MARK3 KO)CVCL_D2KC (Abcam Raji MAT1A KO)CVCL_B7Y7 (Abcam Raji MBD1 KO)
CVCL_B7Y8 (Abcam Raji MBD3 KO)CVCL_D2KD (Abcam Raji ME2 KO)CVCL_D2KE (Abcam Raji MMACHC KO)
CVCL_B7Y9 (Abcam Raji MME KO)CVCL_B7YA (Abcam Raji MMP13 KO)CVCL_B7YB (Abcam Raji MMP8 KO)
CVCL_D2KF (Abcam Raji MPG KO)CVCL_B7YC (Abcam Raji MS4A1 KO)CVCL_B7YD (Abcam Raji MTA3 KO)
CVCL_D2KG (Abcam Raji MTHFR KO)CVCL_D2KH (Abcam Raji NAPRT KO)CVCL_D2KI (Abcam Raji NAT1 KO)
CVCL_B7YE (Abcam Raji NBR1 KO)CVCL_D2KJ (Abcam Raji NCOA5 KO)CVCL_B7YF (Abcam Raji NCR3LG1 KO)
CVCL_D2KK (Abcam Raji NDUFA12 KO)CVCL_D2KL (Abcam Raji NDUFAF2 KO)CVCL_D2KM (Abcam Raji NDUFB6 KO)
CVCL_D2KN (Abcam Raji NDUFB8 KO)CVCL_D2KP (Abcam Raji NDUFS1 KO)CVCL_D2KQ (Abcam Raji NDUFS2 KO)
CVCL_B7YG (Abcam Raji NFATC2 KO)CVCL_B7YH (Abcam Raji NFKB1 KO)CVCL_D2KR (Abcam Raji NFKBIA KO)
CVCL_D2KS (Abcam Raji NFKBIB KO)CVCL_B7YI (Abcam Raji NLRC4 KO)CVCL_D2KT (Abcam Raji NMNAT1 KO)
CVCL_D2KU (Abcam Raji NMT1 KO)CVCL_D2KV (Abcam Raji NMT2 KO)CVCL_D2KW (Abcam Raji NOD2 KO)
CVCL_B7YJ (Abcam Raji NOTCH3 KO)CVCL_B7YK (Abcam Raji NOTCH4 KO)CVCL_D2KX (Abcam Raji NOX5 KO)
CVCL_D2KY (Abcam Raji NPEPPS KO)CVCL_D2KZ (Abcam Raji NQO2 KO)CVCL_B7YL (Abcam Raji NR1H4 KO)
CVCL_B7YM (Abcam Raji NR3C2 KO)CVCL_D2L0 (Abcam Raji NUCB2 KO)CVCL_D2L1 (Abcam Raji OAT KO)
CVCL_D2L2 (Abcam Raji OXSR1 KO)CVCL_D2L3 (Abcam Raji P3H1 KO)CVCL_D2L4 (Abcam Raji PADI2 KO)
CVCL_D2L5 (Abcam Raji PAICS KO)CVCL_D2L6 (Abcam Raji PCMT1 KO)CVCL_D2L7 (Abcam Raji PCYT2 KO)
CVCL_B7YN (Abcam Raji PDCD1LG2 KO)CVCL_D2L8 (Abcam Raji PDHB KO)CVCL_D2L9 (Abcam Raji PDHX KO)
CVCL_D2LA (Abcam Raji PEF1 KO)CVCL_D2LB (Abcam Raji PGAM1 KO)CVCL_D2LC (Abcam Raji PGRMC1 KO)
CVCL_B7YP (Abcam Raji PHF8 KO)CVCL_D2LD (Abcam Raji PI4KB KO)CVCL_B7YQ (Abcam Raji PIK3CA KO)
CVCL_B7YR (Abcam Raji PIK3CD KO)CVCL_B7YS (Abcam Raji PIK3R4 KO)CVCL_D2LE (Abcam Raji PIM2 KO)
CVCL_D2LF (Abcam Raji PKLR KO)CVCL_B7YT (Abcam Raji PLA2G4A KO)CVCL_B7YU (Abcam Raji PLCB3 KO)
CVCL_B7YV (Abcam Raji PLCG1 KO)CVCL_D2LG (Abcam Raji PLIN3 KO)CVCL_D2LH (Abcam Raji PMVK KO)
CVCL_D2LI (Abcam Raji PNMT KO)CVCL_D2LJ (Abcam Raji POLH KO)CVCL_D2LK (Abcam Raji PPOX KO)
CVCL_D2LL (Abcam Raji PPP2CB KO)CVCL_D2LM (Abcam Raji PRG2 KO)CVCL_D2LN (Abcam Raji PRKAB1 KO)
CVCL_D2LP (Abcam Raji PRKACA KO)CVCL_D2LQ (Abcam Raji PRKAG1 KO)CVCL_D2LR (Abcam Raji PRKCG KO)
CVCL_D2LS (Abcam Raji PRKD1 KO)CVCL_B7YW (Abcam Raji PRMT7 KO)CVCL_D2LT (Abcam Raji PRSS8 KO)
CVCL_B7YX (Abcam Raji PSEN1 KO)CVCL_D2LU (Abcam Raji PSMF1 KO)CVCL_B7YY (Abcam Raji PTGER4 KO)
CVCL_B7YZ (Abcam Raji PTGES2 KO)CVCL_B7Z0 (Abcam Raji PTK2 KO)CVCL_B7Z1 (Abcam Raji PTP4A3 KO)
CVCL_D2LV (Abcam Raji PTPA KO)CVCL_B7Z2 (Abcam Raji PTPN12 KO)CVCL_B7Z3 (Abcam Raji PUS1 KO)
CVCL_D2LW (Abcam Raji PYCR1 KO)CVCL_D2LX (Abcam Raji QDPR KO)CVCL_B7Z4 (Abcam Raji RAC2 KO)
CVCL_D2LY (Abcam Raji RECQL KO)CVCL_D2LZ (Abcam Raji REEP5 KO)CVCL_B7Z5 (Abcam Raji RING1 KO)
CVCL_B7Z6 (Abcam Raji ROCK2 KO)CVCL_B7Z7 (Abcam Raji ROR2 KO)CVCL_D2M0 (Abcam Raji RPIA KO)
CVCL_D2M1 (Abcam Raji RXRB KO)CVCL_B7Z8 (Abcam Raji RYBP KO)CVCL_B7Z9 (Abcam Raji SCARB1 KO)
CVCL_B7ZA (Abcam Raji SDC4 KO)CVCL_D2M2 (Abcam Raji SELENOP KO)CVCL_D2M3 (Abcam Raji SERPINB9 KO)
CVCL_B7ZB (Abcam Raji SETD2 KO)CVCL_D2M4 (Abcam Raji SLAMF6 KO)CVCL_D2M5 (Abcam Raji SLC25A12 KO)
CVCL_D2M6 (Abcam Raji SLC5A1 KO)CVCL_B7ZC (Abcam Raji SLFN11 KO)CVCL_D2M7 (Abcam Raji SLK KO)
CVCL_B7ZD (Abcam Raji SMARCAL1 KO)CVCL_B7ZE (Abcam Raji SMARCC2 KO)CVCL_B7ZF (Abcam Raji SMARCE1 KO)
CVCL_D2M8 (Abcam Raji SMS KO)CVCL_B7ZG (Abcam Raji SMURF1 KO)CVCL_B7ZH (Abcam Raji SMYD2 KO)
CVCL_B7ZI (Abcam Raji SMYD3 KO)CVCL_B7ZJ (Abcam Raji SOCS3 KO)CVCL_D2M9 (Abcam Raji SORD KO)
CVCL_D2MA (Abcam Raji SPAG9 KO)CVCL_D2MB (Abcam Raji SPTLC2 KO)CVCL_B7ZK (Abcam Raji SRF KO)
CVCL_B7ZL (Abcam Raji SRPK1 KO)CVCL_D2MC (Abcam Raji SRSF4 KO)CVCL_D2MD (Abcam Raji SSTR2 KO)
CVCL_B7ZM (Abcam Raji STAT4 KO)CVCL_B7ZN (Abcam Raji STAT5A KO)CVCL_D2ME (Abcam Raji STK17B KO)
CVCL_B7ZP (Abcam Raji STK4 KO)CVCL_B7ZQ (Abcam Raji SUV39H1 KO)CVCL_B7ZR (Abcam Raji SUZ12 KO)
CVCL_D2MF (Abcam Raji TACR1 KO)CVCL_B7ZS (Abcam Raji TAPBP KO)CVCL_B7ZT (Abcam Raji TBK1 KO)
CVCL_D2MG (Abcam Raji TBL1XR1 KO)CVCL_B7ZU (Abcam Raji TBP KO)CVCL_B7ZV (Abcam Raji TCF7L2 KO)
CVCL_D2MH (Abcam Raji TDP1 KO)CVCL_D2MI (Abcam Raji TEC KO)CVCL_B7ZW (Abcam Raji TFDP1 KO)
CVCL_D2MJ (Abcam Raji THOP1 KO)CVCL_B7ZX (Abcam Raji TIMP3 KO)CVCL_D2MK (Abcam Raji TLE3 KO)
CVCL_B7ZY (Abcam Raji TLN1 KO)CVCL_B7ZZ (Abcam Raji TNFRSF10B KO)CVCL_B8A0 (Abcam Raji TNFRSF1B KO)
CVCL_D2ML (Abcam Raji TNFSF9 KO)CVCL_B8A1 (Abcam Raji TP73 KO)CVCL_D2MM (Abcam Raji TPD52 KO)
CVCL_D2MN (Abcam Raji TPMT KO)CVCL_D2MP (Abcam Raji TPP1 KO)CVCL_D2MQ (Abcam Raji TPP2 KO)
CVCL_B8A2 (Abcam Raji TRADD KO)CVCL_B8A3 (Abcam Raji TRAF2 KO)CVCL_B8A4 (Abcam Raji TRMT2A KO)
CVCL_D2MR (Abcam Raji TRPC3 KO)CVCL_D2MS (Abcam Raji TRPM2 KO)CVCL_B8A5 (Abcam Raji TWIST1 KO)
CVCL_B8A6 (Abcam Raji TWIST2 KO)CVCL_B8A7 (Abcam Raji U2AF1 KO)CVCL_D2MT (Abcam Raji UAP1 KO)
CVCL_B8A8 (Abcam Raji UBA1 KO)CVCL_B8A9 (Abcam Raji UBE2D2 KO)CVCL_D2MU (Abcam Raji UBE2T KO)
CVCL_D2MV (Abcam Raji UBR1 KO)CVCL_B8AA (Abcam Raji UCHL5 KO)CVCL_B8AB (Abcam Raji ULBP3 KO)
CVCL_D2MW (Abcam Raji UNC119 KO)CVCL_D2MX (Abcam Raji UPP1 KO)CVCL_B8AC (Abcam Raji UVRAG KO)
CVCL_B8AD (Abcam Raji VAV1 KO)CVCL_B8AE (Abcam Raji VCAN KO)CVCL_D2MY (Abcam Raji VDAC2 KO)
CVCL_D2MZ (Abcam Raji VPS37A KO)CVCL_D2N0 (Abcam Raji WAS KO)CVCL_B8AF (Abcam Raji WDR77 KO)
CVCL_B8AG (Abcam Raji WNT11 KO)CVCL_D2N1 (Abcam Raji XPNPEP1 KO)CVCL_B8AH (Abcam Raji YTHDC2 KO)
CVCL_B8AI (Abcam Raji YTHDF1 KO)CVCL_B8AJ (Abcam Raji YTHDF3 KO)CVCL_B8AK (Abcam Raji YY1 KO)
CVCL_B8AL (Abcam Raji ZEB2 KO)CVCL_0R19 (B-THP-1)CVCL_B3QL (MTX-RAJI)
CVCL_3042 (NC-37)CVCL_UJ11 (R/ADR)CVCL_UJ12 (R/VP-16)
CVCL_2699 (RAJI 'A')CVCL_Y035 (Raji 6-TGR)CVCL_C3CD (Raji B2M KO)
CVCL_YN94 (Raji CD19 Knockout)CVCL_2700 (RAJI TK+)CVCL_2701 (RAJI TK-)
CVCL_A7ZV (Raji-h4-1BB)CVCL_A7ZW (Raji-hCTLA4)CVCL_A7ZX (Raji-hEGFR)
CVCL_A7ZY (Raji-HER2)CVCL_A7ZZ (Raji-hICOS)CVCL_A8AA (Raji-hLAG3)
CVCL_A8AC (Raji-hOX40)CVCL_A8AD (Raji-hPD-1)CVCL_A8AE (Raji-hPD-L1)
CVCL_A8AF (Raji-hTIGIT)CVCL_A8AG (Raji-hVISTA)CVCL_C9CV (Raji-Luc2)
CVCL_A8AB (Raji-Null)CVCL_VL72 (Raji(A44))CVCL_LK62 (Raji-GFP)
CVCL_DD98 (Raji-TG)CVCL_KU31 (Raji/18V)CVCL_C0HU (Raji/A)
CVCL_0R22 (Raji/DC-SIGN)CVCL_D2QP (RCC-1)CVCL_3414 (Rj2.2.5)
CVCL_ZI13 (RUD)CVCL_C5DL (sfRaji)CVCL_8431 (TDL-4)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
STR profile Source(s): AddexBio; ATCC; CCRID; CLS; Cosmic-CLP; DSMZ; ECACC; Genomics_Center_BCF_Technion; JCRB; PubMed=11416159; PubMed=25877200; RCB; TKG

Markers:
AmelogeninX,Y
CSF1PO10,12
D1S165614
D2S44111,12
D2S133822 (CCRID; Genomics_Center_BCF_Technion)
21,22 (DSMZ)
D3S135815,16
D5S81810,13
D7S82010
D8S117914,15
D10S124812,13
D12S39118,19
D13S31713
D16S5398,11
D18S5117
D19S43314,14.2 (CCRID; Genomics_Center_BCF_Technion)
14,15 (DSMZ)
D21S1128,31
D22S104515,18
DYS39110
FGA19,27
Penta D3.2,9 (CLS; Genomics_Center_BCF_Technion; PubMed=25877200)
3.2,9,10 (DSMZ)
Penta E5,13
TH016,7
TPOX8,13
vWA16,19

Run an STR similarity search on this cell line
Web pages https://en.wikipedia.org/wiki/Raji_cell
https://www.atcc.org/en/support/technical-support/faqs/ccl-86-morphology-and-growth
http://genome.ucsc.edu/ENCODE/protocols/cell/human/Raji_Farnham_protocol.pdf
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/r/cell-lines-detail-27.html
https://tcpaportal.org/mclp/
Publications

PubMed=14086209; DOI=10.1016/S0140-6736(64)92345-1
Pulvertaft R.J.V.
Cytology of Burkitt's tumour (African lymphoma).
Lancet 283:238-240(1964)

PubMed=4169243; DOI=10.1093/jnci/39.5.1027
Klein G., Clifford P., Klein E., Smith R.T., Minowada J., Kourilsky F.M., Burchenal J.H.
Membrane immunofluorescence reactions of Burkitt lymphoma cells from biopsy specimens and tissue cultures.
J. Natl. Cancer Inst. 39:1027-1044(1967)

PubMed=6018567
Miles C.P., O'Neill F.
Chromosome studies of 8 in vitro lines of Burkitt's lymphoma.
Cancer Res. 27:392-402(1967)

PubMed=4894370; DOI=10.1002/1097-0142(196908)24:2<211::AID-CNCR2820240202>3.0.CO;2-3
Southam C.M., Burchenal J.H., Clarkson B.D. Sr., Tanzi A., Mackey R., McComb V.
Heterotransplantability of human cell lines derived from leukemia and lymphomas into immunologically tolerant rats.
Cancer 24:211-222(1969)

DOI=10.1007/BF02618370
Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.
The animal cell culture collection.
In Vitro 5:1-16(1970)

PubMed=4321017; DOI=10.1002/ijc.2910060315
Durr F.E., Monroe J.H., Schmitter R., Traul K.A., Hirshaut Y.
Studies on the infectivity and cytopathology of Epstein-Barr virus in human lymphoblastoid cells.
Int. J. Cancer 6:436-449(1970)

PubMed=4321974
Maurer B.A., Imamura T., Wilbert S.M.
Incidence of EB virus-containing cells in primary and secondary clones of several Burkitt lymphoma cell lines.
Cancer Res. 30:2870-2875(1970)

PubMed=4325933; DOI=10.1093/jnci/46.6.1243
Pearson G.R., Henle G., Henle W.
Production of antigens associated with Epstein-Barr virus in experimentally infected lymphoblastoid cell lines.
J. Natl. Cancer Inst. 46:1243-1250(1971)

PubMed=4122458; DOI=10.1002/ijc.2910100108
Klein G., Dombos L., Gothoskar B.
Sensitivity of Epstein-Barr virus (EBV) producer and non-producer human lymphoblastoid cell lines to superinfection with EB-virus.
Int. J. Cancer 10:44-57(1972)

PubMed=4347031; DOI=10.1093/jnci/48.1.87
Hewetson J.F., Gothoskar B., Klein G.
Radioiodine-labeled antibody test for the detection of membrane antigens associated with Epstein-Barr virus.
J. Natl. Cancer Inst. 48:87-94(1972)

PubMed=4550511; DOI=10.1073/pnas.69.1.78
Hampar B., Derge J.G., Martos L.M., Walker J.L.
Synthesis of Epstein-Barr virus after activation of the viral genome in a 'virus-negative' human lymphoblastoid cell (Raji) made resistant to 5-bromodeoxyuridine.
Proc. Natl. Acad. Sci. U.S.A. 69:78-82(1972)

PubMed=4364259; DOI=10.1002/ijc.2910110210
Klein G., Dombos L.
Relationship between the sensitivity of EBV-carrying lymphoblastoid lines to superinfection and the inducibility of the resident viral genome.
Int. J. Cancer 11:327-337(1973)

PubMed=4736620; DOI=10.1111/j.1469-1809.1973.tb00588.x
Povey S., Gardiner S.E., Watson B., Mowbray S., Harris H., Arthur E., Steel C.M., Blenkinsop C., Evans H.J.
Genetic studies on human lymphoblastoid lines: isozyme analysis on cell lines from forty-one different individuals and on mutants produced following exposure to a chemical mutagen.
Ann. Hum. Genet. 36:247-266(1973)

PubMed=4366935
Minowada J., Nonoyama M., Moore G.E., Rauch A.M., Pagano J.S.
The presence of the Epstein-Barr viral genome in human lymphoblastoid B-cell lines and its absence in a myeloma cell line.
Cancer Res. 34:1898-1903(1974)

PubMed=170370; DOI=10.1099/0022-1317-28-2-207
Adams A., Strander H., Cantell K.
Sensitivity of the Epstein-Barr virus transformed human lymphoid cell lines to interferon.
J. Gen. Virol. 28:207-217(1975)

PubMed=1086134
Kaplan J., Peterson W.D. Jr.
Detection of T-cell lymphoma-associated antigens on cord blood lymphocytes and phytohemagglutinin-stimulated blasts.
Cancer Res. 36:3471-3475(1976)

PubMed=216485
Higgins N.P., Strauss B.S.
Differences in the ability of human lymphoblastoid lines to exclude bromodeoxyuridine and in their sensitivity to methyl methanesulfonate and to incorporated [3H]thymidine.
Cancer Res. 39:312-320(1979)

PubMed=7316467; DOI=10.1111/j.1469-1809.1980.tb00953.x
Povey S., Jeremiah S., Arthur E., Steel M., Klein G.
Differences in genetic stability between human cell lines from patients with and without lymphoreticular malignancy.
Ann. Hum. Genet. 44:119-133(1980)

PubMed=6265077
Pizzo P.A., Chattopadhyay S.K., Magrath I.T., Del Giacco E., Sherrick D., Gray T.
Examination of Epstein-Barr virus and C-type proviral sequences in American and African lymphomas and derivative cell lines.
Cancer Res. 41:3165-3171(1981)

PubMed=6286763; DOI=10.4049/jimmunol.129.3.1336
Benjamin D., Magrath I.T., Maguire R.T., Janus C., Todd H.D., Parsons R.G.
Immunoglobulin secretion by cell lines derived from African and American undifferentiated lymphomas of Burkitt's and non-Burkitt's type.
J. Immunol. 129:1336-1342(1982)

PubMed=6806672; DOI=10.1038/298474a0
Lenoir G.M., Preud'homme J.-L., Bernheim A., Berger R.
Correlation between immunoglobulin light chain expression and variant translocation in Burkitt's lymphoma.
Nature 298:474-476(1982)

PubMed=6954533; DOI=10.1073/pnas.79.7.2194
Westin E.H., Gallo R.C., Arya S.K., Eva A., Souza L.M., Baluda M.A., Aaronson S.A., Wong-Staal F.
Differential expression of the amv gene in human hematopoietic cells.
Proc. Natl. Acad. Sci. U.S.A. 79:2194-2198(1982)

PubMed=7060222; DOI=10.1016/0009-2797(82)90007-2
Meltz M.L., Whittam N.J., Thornburg W.H.
Reassociation of human lymphoblastoid cell DNA repair replicated following methyl methanesulfonate treatment.
Chem. Biol. Interact. 39:77-88(1982)

PubMed=6306472; DOI=10.1038/304135a0
Hamlyn P.H., Rabbitts T.H.
Translocation joins c-myc and immunoglobulin gamma 1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene.
Nature 304:135-139(1983)

PubMed=6419122; DOI=10.1038/306760a0
Rabbitts T.H., Hamlyn P.H., Baer R.
Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma.
Nature 306:760-765(1983)

PubMed=6600440; DOI=10.1007/BF02617996
Uittenbogaart C.H., Cantor Y., Fahey J.L.
Growth of human malignant lymphoid cell lines in serum-free medium.
In Vitro 19:67-72(1983)

PubMed=6231253; DOI=10.1002/ijc.2910330407
Ehlin-Henriksson B., Klein G.
Distinction between Burkitt lymphoma subgroups by monoclonal antibodies: relationships between antigen expression and type of chromosomal translocation.
Int. J. Cancer 33:459-463(1984)

PubMed=6500159; DOI=10.1159/000163283
Gershwin M.E., Lentz D., Owens R.B.
Relationship between karyotype of tissue culture lines and tumorigenicity in nude mice.
Exp. Cell Biol. 52:361-370(1984)

PubMed=6547209; DOI=10.1038/309592a0
Rabbitts T.H., Forster A., Hamlyn P.H., Baer R.
Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma.
Nature 309:592-597(1984)

PubMed=6582512; DOI=10.1073/pnas.81.2.568
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

PubMed=6592381; DOI=10.1093/jnci/73.4.841
Favrot M.-C., Philip I., Philip T., Portoukalian J., Dore J.-F., Lenoir G.M.
Distinct reactivity of Burkitt's lymphoma cell lines with eight monoclonal antibodies correlated with the ethnic origin.
J. Natl. Cancer Inst. 73:841-847(1984)

PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cell lines -- 1 carboxylic esterase.
Leuk. Res. 9:209-229(1985)

PubMed=2998993
Steel C.M., Morten J.E.N., Foster E.
The cytogenetics of human B lymphoid malignancy: studies in Burkitt's lymphoma and Epstein-Barr virus-transformed lymphoblastoid cell lines.
IARC Sci. Publ. 60:265-292(1985)

PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cell lines -- III Beta-hexosaminidase (E.C. 3.2.1.30).
Leuk. Res. 9:549-559(1985)

PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid phosphatase.
Leuk. Res. 9:537-548(1985)

PubMed=3905596
Favrot M.-C., Philip I., Philip T., Cabrillat H., Pinatel C., Dore J.-F., Lenoir G.M.
Immunophenotypic classification of 28 Burkitt cell lines with monoclonal antibodies and reagent selection for bone-marrow purging.
IARC Sci. Publ. 60:447-452(1985)

PubMed=3080238
Sieverts H., Alabaster O., Goldschmidts W., Magrath I.T.
Expression of surface antigens during the cell cycle in different growth phases of American and African Burkitt's lymphoma cell lines.
Cancer Res. 46:1182-1188(1986)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=3026973; DOI=10.1002/ijc.2910390215
Ehlin-Henriksson B., Manneborg-Sandlund A., Klein G.
Expression of B-cell-specific markers in different Burkitt lymphoma subgroups.
Int. J. Cancer 39:211-218(1987)

PubMed=3034807; DOI=10.1002/ijc.2910390622
Ohno H., Fukuhara S., Takahashi R., Mihara K.-i., Sugiyama T., Doi S., Uchino H., Toyoshima K.
c-yes and bcl-2 genes located on 18q21.3 in a follicular lymphoma cell line carrying a t(14;18) chromosomal translocation.
Int. J. Cancer 39:785-788(1987)

PubMed=2470097; DOI=10.1073/pnas.86.9.3257
Shtivelman E., Henglein B., Groitl P., Lipp M., Bishop J.M.
Identification of a human transcription unit affected by the variant chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.
Proc. Natl. Acad. Sci. U.S.A. 86:3257-3260(1989)

PubMed=2140233; DOI=10.1111/j.1440-1827.1990.tb01549.x
Nakano A., Harada T., Morikawa S., Kato Y.
Expression of leukocyte common antigen (CD45) on various human leukemia/lymphoma cell lines.
Acta Pathol. Jpn. 40:107-115(1990)

PubMed=1915267; DOI=10.1002/j.1460-2075.1991.tb07837.x
Farrell P.J., Allan G.J., Shanahan F., Vousden K.H., Crook T.
p53 is frequently mutated in Burkitt's lymphoma cell lines.
EMBO J. 10:2879-2887(1991)

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992)

CLPUB00458
Treichel R.S.
Susceptibility to LAK-mediated cytotoxicity of multidrug-resistant variants of the human RAJI cell line is not related to expression of major cellular adhesion molecules.
Ohio J. Sci. 93:14-18(1993)

PubMed=8316623; DOI=10.2307/3578190
Evans H.H., Ricanati M., Horng M.-F., Jiang Q.-Y., Mencl J., Olive P.L.
DNA double-strand break rejoining deficiency in TK6 and other human B-lymphoblast cell lines.
Radiat. Res. 134:307-315(1993)

PubMed=8344493; DOI=10.1096/fasebj.7.10.8344493
Bhatia K.G., Goldschmidts W., Gutierrez M.I., Gaidano G., Dalla-Favera R., Magrath I.T.
Hemi- or homozygosity: a requirement for some but not other p53 mutant proteins to accumulate and exert a pathogenetic effect.
FASEB J. 7:951-956(1993)

PubMed=8515068; DOI=10.4049/jimmunol.150.12.5418
Jain V.K., Judde J.-G., Max E.E., Magrath I.T.
Variable IgH chain enhancer activity in Burkitt's lymphomas suggests an additional, direct mechanism of c-myc deregulation.
J. Immunol. 150:5418-5428(1993)

PubMed=7849311; DOI=10.1182/blood.V85.4.893.bloodjournal854893
Stranks G., Height S.E., Mitchell P., Jadayel D.M., Yuille M.A.R., De Lord C., Clutterbuck R.D., Treleaven J.G., Powles R.L., Nacheva E., Oscier D.G., Karpas A., Lenoir G.M., Smith S.D., Millar J.L., Catovsky D., Dyer M.J.S.
Deletions and rearrangement of CDKN2 in lymphoid malignancy.
Blood 85:893-901(1995)

PubMed=8547074; DOI=10.1111/j.1365-2141.1995.tb05302.x
Siebert R., Willers C.P., Schramm A., Fossa A., Dresen I.M.G., Uppenkamp M., Nowrousian M.R., Seeber S., Opalka B.
Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukaemia cell lines.
Br. J. Haematol. 91:350-354(1995)

PubMed=8558913
Morita S., Tsuchiya S., Fujie H., Itano M., Ohashi Y., Minegishi M., Imaizumi M., Endo M., Takano N., Konno T.
Cell surface c-kit receptors in human leukemia cell lines and pediatric leukemia: selective preservation of c-kit expression on megakaryoblastic cell lines during adaptation to in vitro culture.
Leukemia 10:102-105(1996)

PubMed=8847894
Tani A., Tatsumi E., Nakamura F., Kumagai S., Kosaka Y., Sano K., Nakamura H., Amakawa R., Ohno H.
Sensitivity to dexamethasone and absence of bcl-2 protein in Burkitt's lymphoma cell line (Black93) derived from a patient with acute tumor lysis syndrome: comparative study with other BL and non-BL lines.
Leukemia 10:1592-1603(1996)

PubMed=9192833
Cherney B.W., Bhatia K.G., Sgadari C., Gutierrez M.I., Mostowski H.S., Pike S.E., Gupta G., Magrath I.T., Tosato G.
Role of the p53 tumor suppressor gene in the tumorigenicity of Burkitt's lymphoma cells.
Cancer Res. 57:2508-2515(1997)

PubMed=9473234; DOI=10.1182/blood.V91.5.1680
Klangby U., Okan I., Magnusson K.P., Wendland M., Lind P., Wiman K.G.
p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma.
Blood 91:1680-1687(1998)

PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x
Hosoya N., Hangaishi A., Ogawa S., Miyagawa K., Mitani K., Yazaki Y., Hirai H.
Frameshift mutations of the hMSH6 gene in human leukemia cell lines.
Jpn. J. Cancer Res. 89:33-39(1998)

PubMed=9685479; DOI=10.1093/nar/26.16.3651
Hultdin M., Gronlund E., Norrback K.-F., Eriksson-Lindstrom E., Just T., Roos G.
Telomere analysis by fluorescence in situ hybridization and flow cytometry.
Nucleic Acids Res. 26:3651-3656(1998)

PubMed=9737686; DOI=10.1038/sj.leu.2401112
Zhang W., Ohnishi K., Shigeno K., Fujisawa S., Naito K., Nakamura S., Takeshita K., Takeshita A., Ohno R.
The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms.
Leukemia 12:1383-1391(1998)

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x
Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T., Aizawa Y., Ueda R., Seto M.
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.
Jpn. J. Cancer Res. 89:712-718(1998)

PubMed=9787181; DOI=10.1182/blood.V92.9.3410
Sakai A., Thieblemont C., Wellmann A., Jaffe E.S., Raffeld M.
PTEN gene alterations in lymphoid neoplasms.
Blood 92:3410-3415(1998)

PubMed=9973220
Gutierrez M.I., Cherney B.W., Hussain A., Mostowski H.S., Tosato G., Magrath I.T., Bhatia K.G.
Bax is frequently compromised in Burkitt's lymphomas with irreversible resistance to Fas-induced apoptosis.
Cancer Res. 59:696-703(1999)

PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.
Leuk. Res. 24:255-262(2000)

PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000),255-262.
Leuk. Res. 25:275-278(2001)

PubMed=11416159; DOI=10.1073/pnas.121616198
Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=12145705; DOI=10.1038/sj.leu.2402519
Langerak A.W., Moreau E., van Gastel-Mol E.J., van der Burg M., van Dongen J.J.M.
Detection of clonal EBV episomes in lymphoproliferations as a diagnostic tool.
Leukemia 16:1572-1573(2002)

PubMed=12967475; DOI=10.1111/j.1349-7006.2003.tb01518.x
Maesako Y., Uchiyama T., Ohno H.
Comparison of gene expression profiles of lymphoma cell lines from transformed follicular lymphoma, Burkitt's lymphoma and de novo diffuse large B-cell lymphoma.
Cancer Sci. 94:774-781(2003)

PubMed=14982850; DOI=10.1016/S0002-9440(10)63184-7
Takakuwa T., Luo W.-J., Ham M.F., Sakane-Ishikawa E., Wada N., Aozasa K.
Integration of Epstein-Barr virus into chromosome 6q15 of Burkitt lymphoma cell line (Raji) induces loss of BACH2 expression.
Am. J. Pathol. 164:967-974(2004)

PubMed=15028022; DOI=10.1111/j.1440-1827.2004.01612.x
Kamimura K., Hojo H., Abe M.
Characterization of expression of protein kinase C isozymes in human B-cell lymphoma: relationship between its expression and prognosis.
Pathol. Int. 54:224-230(2004)

PubMed=15457187; DOI=10.1038/sj.leu.2403534
Karpova M.B., Schoumans J., Ernberg I., Henter J.-I., Nordenskjold M., Fadeel B.
Raji revisited: cytogenetics of the original Burkitt's lymphoma cell line.
Leukemia 19:159-161(2005)

PubMed=15901131; DOI=10.1016/j.prp.2005.01.002
Murai Y., Hayashi S., Takahashi H., Tsuneyama K., Takano Y.
Correlation between DNA alterations and p53 and p16 protein expression in cancer cell lines.
Pathol. Res. Pract. 201:109-115(2005)

PubMed=18357372; DOI=10.3892/or.19.4.889
Pop I., Pop L., Vitetta E.S., Ghetie M.-A.
Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein.
Oncol. Rep. 19:889-895(2008)

PubMed=19358282; DOI=10.1002/ijc.24351
Inagaki A., Ishida T., Yano H., Ishii T., Kusumoto S., Ito A., Ri M., Mori F., Ding J.-M., Komatsu H., Iida S., Ueda R.
Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role in determining their susceptibility to rituximab-induced ADCC.
Int. J. Cancer 125:212-221(2009)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=20454443; DOI=10.1155/2010/904767
Uphoff C.C., Denkmann S.A., Steube K.G., Drexler H.G.
Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II, and SMRV in human and other primate cell lines.
J. Biomed. Biotechnol. 2010:904767.1-904767.23(2010)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=22885699; DOI=10.1038/nature11378
Schmitz R., Young R.M., Ceribelli M., Jhavar S., Xiao W.-M., Zhang M.-L., Wright G., Shaffer A.L. III, Hodson D.J., Buras E., Liu X.-L., Powell J.I., Yang Y.-D., Xu W.-H., Zhao H., Kohlhammer H., Rosenwald A., Kluin P., Muller-Hermelink H.-K., Ott G., Gascoyne R.D., Connors J.M., Rimsza L.M., Campo E., Jaffe E.S., Delabie J., Smeland E.B., Ogwang M.D., Reynolds S.J., Fisher R.I., Braziel R.M., Tubbs R.R., Cook J.R., Weisenburger D.D., Chan W.C., Pittaluga S., Wilson W., Waldmann T.A., Rowe M., Mbulaiteye S.M., Rickinson A.B., Staudt L.M.
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics.
Nature 490:116-120(2012)

PubMed=24590883; DOI=10.1002/gcc.22161
Murga Penas E.-M., Schilling G., Behrmann P., Klokow M., Vettorazzi E., Bokemeyer C., Dierlamm J.
Comprehensive cytogenetic and molecular cytogenetic analysis of 44 Burkitt lymphoma cell lines: secondary chromosomal changes characterization, karyotypic evolution, and comparison with primary samples.
Genes Chromosomes Cancer 53:497-515(2014)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25355872; DOI=10.1128/JVI.02570-14
Cao S.-B., Strong M.J., Wang X., Moss W.N., Concha M., Lin Z., O'Grady T., Baddoo M., Fewell C., Renne R., Flemington E.K.
High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project.
J. Virol. 89:713-729(2015)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=27566572; DOI=10.18632/oncotarget.11524
Quentmeier H., Pommerenke C., Ammerpohl O., Geffers R., Hauer V., MacLeod R.A.F., Nagel S., Romani J., Rosati E., Rosen A., Uphoff C.C., Zaborski M., Drexler H.G.
Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation.
Oncotarget 7:63456-63465(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=29892436; DOI=10.1098/rsos.172472
Shioda S., Kasai F., Watanabe K., Kawakami K., Ohtani A., Iemura M., Ozawa M., Arakawa A., Hirayama N., Kawaguchi E., Tano T., Miyata S., Satoh M., Shimizu N., Kohara A.
Screening for 15 pathogenic viruses in human cell lines registered at the JCRB Cell Bank: characterization of in vitro human cells by viral infection.
R. Soc. Open Sci. 5:172472-172472(2018)

PubMed=30285677; DOI=10.1186/s12885-018-4840-5
Tan K.-T., Ding L.-W., Sun Q.-Y., Lao Z.-T., Chien W., Ren X., Xiao J.-F., Loh X.-Y., Xu L., Lill M., Mayakonda A., Lin D.-C., Yang H., Koeffler H.P.
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
BMC Cancer 18:940.1-940.13(2018)

PubMed=30629668; DOI=10.1371/journal.pone.0210404
Uphoff C.C., Pommerenke C., Denkmann S.A., Drexler H.G.
Screening human cell lines for viral infections applying RNA-Seq data analysis.
PLoS ONE 14:E0210404-E0210404(2019)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) Abcam; ab271145
Abcam; ab275473
AddexBio; C0003009/4668
ATCC; CCL-86
ATCC; CRL-7936 - Discontinued
BCRC; 60116
BCRJ; 0211
CCTCC; GDC0191
CLS; 300359
Coriell; GM04671
DSMZ; ACC-319
ECACC; 85011429
HIVReagentProgram; ARP-9944
ICLC; HTL00002
IZSLER; BS TCL 54
JCRB; IFO50046
JCRB; JCRB9012
NCBI_Iran; C127
RCB; RCB1647
RCB; RCB3673
TKG; TKG 0371
Cell line databases/resources CLO; CLO_0008734
CLO; CLO_0019014
CLO; CLO_0050995
MCCL; MCC:0000409
CLDB; cl4086
CLDB; cl4088
CLDB; cl4089
CLDB; cl4090
CLDB; cl4091
CLDB; cl4092
CLDB; cl4990
cancercelllines; CVCL_0511
CCRID; 1101HUM-PUMC000046
CCRID; 1102HUM-NIFDC00025
CCRID; 3101HUMTCHu44
CCRID; 4201HUM-CCTCC00191
Cell_Model_Passport; SIDM00844
CGH-DB; 9204-4
Cosmic-CLP; 909262
DepMap; ACH-000654
DSMZCellDive; ACC-319
IHW; IHW04994
IGRhCellID; Raji
IPD-IMGT/HLA; 11295
LINCS_LDP; LCL-2025
Lonza; 726
TOKU-E; 2967
Anatomy/cell type resources BTO; BTO:0001154
Biological sample resources BioSample; SAMN01821589
BioSample; SAMN01821656
BioSample; SAMN01821715
BioSample; SAMN01821738
BioSample; SAMN03473128
BioSample; SAMN10987653
ENCODE; ENCBS260AAA
CRISP screens repositories BioGRID_ORCS_Cell_line; 272
Chemistry resources ChEMBL-Cells; CHEMBL3307663
ChEMBL-Targets; CHEMBL614628
GDSC; 909262
PharmacoDB; Raji_1282_2019
PubChem_Cell_line; CVCL_0511
Encyclopedic resources Wikidata; Q4215980
Experimental variables resources EFO; EFO_0002324
Gene expression databases ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2706
ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610
ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
GEO; GSM33154
GEO; GSM99387
GEO; GSM887523
GEO; GSM888605
GEO; GSM1374840
GEO; GSM1374841
GEO; GSM1374842
GEO; GSM1602232
GEO; GSM1602233
GEO; GSM1602234
GEO; GSM1602235
GEO; GSM1602236
GEO; GSM1602237
GEO; GSM1602238
GEO; GSM1602241
GEO; GSM1602242
GEO; GSM1602243
GEO; GSM1602244
GEO; GSM1670357
GEO; GSM3150253
Polymorphism and mutation databases Cosmic; 687850
Cosmic; 850211
Cosmic; 850387
Cosmic; 851997
Cosmic; 909262
Cosmic; 919136
Cosmic; 929816
Cosmic; 931110
Cosmic; 932761
Cosmic; 991549
Cosmic; 998718
Cosmic; 1019313
Cosmic; 1037703
Cosmic; 1070707
Cosmic; 1071883
Cosmic; 1082517
Cosmic; 1093788
Cosmic; 1107179
Cosmic; 1127266
Cosmic; 1176615
Cosmic; 1191688
Cosmic; 1483367
Cosmic; 1517664
Cosmic; 1818346
Cosmic; 2301566
Cosmic; 2361386
Cosmic; 2649241
Cosmic; 2814541
Cosmic; 2815215
Cosmic; 2823074
IARC_TP53; 704
IARC_TP53; 21706
LiGeA; CCLE_651
Progenetix; CVCL_0511
Proteomic databases PRIDE; PXD005704
PRIDE; PXD012087
PRIDE; PXD030304
Sequence databases EGA; EGAS00001000610
EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number47