Cellosaurus cell line RCC-1 (CVCL

Cellosaurus RCC-1 (CVCL_D2QP)

[Text version]

Cell line name

RCC-1

Synonyms

Raji Co-Culture No.1

Accession

CVCL_D2QP

Resource Identification Initiative

To cite this cell line use: RCC-1 (RRID:CVCL_D2QP)

Comments

Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11734.
Population: African; Nigerian.
Virology: Infected with human herpesvirus 8 (HHV-8/KSHV). Produced by the co-cultivation of Raji cells with BC-1 cells (Cellosaurus=CVCL_1079) separated by filter tissue culture inserts to prevent cross-contamination (PubMed=8523568).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Cell type: B-cell; CL=CL_0000236.

Sequence variations

Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).

Disease

EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0511 (Raji)
Children:

CVCL_D2QQ (RCC-1 clone 2F5)

Sex of cell

Male

Age at sampling

11Y