Cellosaurus Raji-APC-hPD-L1 (CVCL_E3JC)
| Cell line name | Raji-APC-hPD-L1 |
|---|---|
| Accession | CVCL_E3JC |
| Resource Identification Initiative | To cite this cell line use: Raji-APC-hPD-L1 (RRID:CVCL_E3JC) |
| Comments | Population: African; Nigerian. Biotechnology: Used in the Jurkat-Raji PD-1/PD-L1 assay (Bio-IC) specifically designed for screening antibody-, Fc-fusion protein-, or small-molecule antagonists of the PD-1/PD-L1 immune checkpoint (IC) axis (Invivogen). Characteristics: Transfected with a specific antigenic peptide complexed with HLA molecules ([HLA::peptide]) (InvivoGen). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:17635; CD274. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397. Cell type: B-cell; CL=CL_0000236. |
| Sequence variations |
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| Disease | EBV-related Burkitt lymphoma (NCIt: C27694) Burkitt lymphoma (ORDO: Orphanet_543) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0511 (Raji) |
| Sex of cell | Male |
| Age at sampling | 11Y |
| Category | Cancer cell line |
| Web pages | https://www.invivogen.com/hpd1-bioassay |
| Entry history | |
| Entry creation | 19-Dec-2024 |
| Last entry update | 19-Dec-2024 |
| Version number | 1 |