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Cellosaurus Raji/A (CVCL_C0HU)

[Text version]
Cell line name Raji/A
Accession CVCL_C0HU
Resource Identification Initiative To cite this cell line use: Raji/A (RRID:CVCL_C0HU)
Comments Population: African; Nigerian.
Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0511 (Raji)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
Publications

PubMed=25916297; DOI=10.3760/cma.j.issn.0253-2727.2015.04.015; PMCID=PMC7342615
Zheng R.-L., Jiang Y.-J., Wang X.
The establishment of Raji drug-resistant cell line and analyses of prohibitin and miR-27a expression.
Zhonghua Xue Ye Xue Za Zhi 36:326-330(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C0HU
Encyclopedic resources Wikidata; Q114312766
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number7