Cellosaurus cell line Raji-APC-Null (CVCL

Cellosaurus Raji-APC-Null (CVCL_E3JB)

Entry history
Cell line name	Raji-APC-Null
Accession	CVCL_E3JB
Resource Identification Initiative	To cite this cell line use: Raji-APC-Null (RRID:CVCL_E3JB)
Comments	Population: African; Nigerian. Biotechnology: Activating control antigen presenting cell (APC) for anti-immune checkpoint cell-based assay (InvivoGen). Characteristics: Transfected with a specific antigenic peptide complexed with HLA molecules ([HLA::peptide]) (InvivoGen). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease	EBV-related Burkitt lymphoma (NCIt: C27694) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0511 (Raji)
Sex of cell	Male
Age at sampling	11Y
Category	Cancer cell line
Web pages	https://www.invivogen.com/raji-apc-null
Entry creation	19-Dec-2024
Last entry update	19-Dec-2024
Version number	1