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Cellosaurus Abcam Raji NOTCH3 KO (CVCL_B7YJ)

[Text version]
Cell line name Abcam Raji NOTCH3 KO
Synonyms Human NOTCH3 knockout Raji
Accession CVCL_B7YJ
Resource Identification Initiative To cite this cell line use: Abcam Raji NOTCH3 KO (RRID:CVCL_B7YJ)
Comments Population: African; Nigerian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 7883; NOTCH3.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Sequence variations
  • Gene fusion; HGNC; 5477; IGH + HGNC; 7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0511 (Raji)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Abcam; ab290316
Encyclopedic resources Wikidata; Q112928845
Entry history
Entry creation23-Jun-2022
Last entry update29-Jun-2023
Version number4