Cellosaurus cell line HyCyte Raji KO-hJAK2 (CVCL

Cross-references
Cell line name	HyCyte Raji KO-hJAK2
Synonyms	hJAK2 knockout Raji
Accession	CVCL_D6CD
Resource Identification Initiative	To cite this cell line use: HyCyte Raji KO-hJAK2 (RRID:CVCL_D6CD)
Comments	Population: African; Nigerian. Doubling time: 24-36 hours (Hysigen=CGKO-M2404). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:6192; JAK2. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease	EBV-related Burkitt lymphoma (NCIt: C27694) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0511 (Raji)
Sex of cell	Male
Age at sampling	11Y
Category	Cancer cell line
Cell line collections (Providers)	Hysigen; CGKO-M2404
Encyclopedic resources	Wikidata; Q127382050
Entry history
Entry creation	02-May-2024
Last entry update	19-Dec-2024
Version number	3