Cellosaurus cell line Raji-Fluc-Puro (CVCL

Cross-references
Cell line name	Raji-Fluc-Puro
Accession	CVCL_D5KN
Resource Identification Initiative	To cite this cell line use: Raji-Fluc-Puro (RRID:CVCL_D5KN)
Comments	Population: African; Nigerian. Characteristics: Reporter cell line, transfected with the LV-Fluc-P2A-Puro vector encoding for luciferase linked via a P2A cleavage peptide to the pac gene and under control of the spleen focus-forming virus (SFFV) promoter (Imanis=CL161). Transfected with: UniProtKB; P08659; Firefly luciferase. Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR). Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Gene fusion; HGNC; 5477; IGH + HGNC; 7553; MYC; Name(s)=MYC-IGH (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease	EBV-related Burkitt lymphoma (NCIt: C27694) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0511 (Raji)
Sex of cell	Male
Age at sampling	11Y
Category	Cancer cell line
Cell line collections (Providers)	Imanis; CL161
Entry history
Entry creation	02-May-2024
Last entry update	02-May-2024
Version number	1