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Cellosaurus Raji 6-TGR (CVCL_Y035)

[Text version]
Cell line name Raji 6-TGR
Accession CVCL_Y035
Resource Identification Initiative To cite this cell line use: Raji 6-TGR (RRID:CVCL_Y035)
Comments Population: African; Nigerian.
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Sequence variations
  • Gene fusion; HGNC; 5477; IGH + HGNC; 7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0511 (Raji)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
Publications

DOI=10.2177/jsci.11.346
Ikewaki N.
Establishment of a 6-thioguanine (6-TG)-neo-resistant mutant human lymphoma cell line.
Jpn. J. Clin. Immunol. 11:346-356(1988)

Cross-references
Encyclopedic resources Wikidata; Q54949146
Entry history
Entry creation07-Nov-2014
Last entry update29-Jun-2023
Version number16