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Cellosaurus Raji-Fluc-EmGFP (CVCL_D5KM)

[Text version]
Cell line name Raji-Fluc-EmGFP
Accession CVCL_D5KM
Resource Identification Initiative To cite this cell line use: Raji-Fluc-EmGFP (RRID:CVCL_D5KM)
Comments Population: African; Nigerian.
Characteristics: Reporter cell line, transduced with the LV-SFFV-Luc2-P2A-EmGFP vector encoding for luciferase linked via a P2A cleavage site to emerald GFP (EmGFP) and under control of the spleen focus-forming virus (SFFV) promoter (Imanis=CL159).
Genetic integration: Method=Transduction; Gene=FPbase; GLAD6; Emerald (Note=EmGFP, green fluorescent protein derived from GFP).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Misspelling: Raji-Fluc-eGFP; Imanis=CL159; Note=In old versions.
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0511 (Raji)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Imanis; CL159
Encyclopedic resources Wikidata; Q127384003
Entry history
Entry creation02-May-2024
Last entry update19-Dec-2024
Version number3