• Mutation; HGNC; 11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Heterozygous (PubMed=8504475).
  
• Mutation; HGNC; 11998; TP53; Simple; p.Arg282Trp (c.843_844CC>TT); Zygosity=Heterozygous (PubMed=8504475).
  

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Lehman T.A., Modali R.V., Boukamp P., Stanek J., Bennett W.P., Welsh J.A., Metcalf R.A., Stampfer M.R., Fusenig N.E., Rogan E.M., Harris C.C.
p53 mutations in human immortalized epithelial cell lines.
Carcinogenesis 14:833-839(1993)

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Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
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Altenburger R., Kissel T.
The human keratinocyte cell line HaCaT: an in vitro cell culture model for keratinocyte testosterone metabolism.
Pharm. Res. 16:766-771(1999)

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Boukamp P., Popp S., Bleuel K., Tomakidi E., Burkle A., Fusenig N.E.
Tumorigenic conversion of immortal human skin keratinocytes (HaCaT) by elevated temperature.
Oncogene 18:5638-5645(1999)

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Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

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Mueller M.M., Peter W., Mappes M., Huelsen A., Steinbauer H., Boukamp P., Vaccariello M.A., Garlick J.A., Fusenig N.E.
Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor.
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Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis.
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Olaru F., Jensen L.E.
Chemokine expression by human keratinocyte cell lines after activation of Toll-like receptors.
Exp. Dermatol. 19:e314-e316(2010)

PubMed=21185708; DOI=10.1016/j.jnutbio.2010.08.004
Serini S., Donato V., Piccioni E., Trombino S., Monego G., Toesca A., Innocenti I., Missori M., De Spirito M., Celleno L., Fasano E., Ranelletti F.O., Calviello G.
Docosahexaenoic acid reverts resistance to UV-induced apoptosis in human keratinocytes: involvement of COX-2 and HuR.
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Initial characterization of the human central proteome.
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PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
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Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

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Wilson V.G.
Growth and differentiation of HaCaT keratinocytes.
Methods Mol. Biol. 1195:33-41(2014)

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Elbediwy A., Vincent-Mistiaen Z.I., Spencer-Dene B., Stone R.K., Boeing S., Wculek S.K., Cordero J., Tan E.H., Ridgway R., Brunton V.G., Sahai E., Gerhardt H., Behrens A., Malanchi I., Sansom O.J., Thompson B.J.
Integrin signalling regulates YAP and TAZ to control skin homeostasis.
Development 143:1674-1687(2016)

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Himmelsbach K., Hildt E.
Identification of various cell culture models for the study of Zika virus.
World J. Virol. 7:10-20(2018)

PubMed=29660373; DOI=10.1016/j.bbagen.2018.04.012
Touat-Hamici Z., Bulteau A.-L., Bianga J., Jean-Jacques H., Szpunar J., Lobinski R., Chavatte L.
Selenium-regulated hierarchy of human selenoproteome in cancerous and immortalized cells lines.
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PubMed=31629070; DOI=10.1016/j.tiv.2019.104666
da Silva A.C.G., Chialchia A.R., de Castro E.G., e Silva M.R.L., Arantes D.A.C., Batista A.C., Kitten G.T., Valadares M.C.
A new corneal epithelial biomimetic 3D model for in vitro eye toxicity assessment: development, characterization and applicability.
Toxicol. In Vitro 62:104666.1-104666.7(2020)

PubMed=32938951; DOI=10.1038/s41598-020-71315-0; PMCID=PMC7494900
Pavez Lorie E., Stricker N., Plitta-Michalak B.P., Chen I.-P., Volkmer B., Greinert R., Jauch A., Boukamp P., Rapp A.
Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw.
Sci. Rep. 10:15196-15196(2020)

PubMed=33718544; DOI=10.1016/j.dib.2021.106871; PMCID=PMC7921465
Rusanov A.L., Romashin D.D., Zgoda V.G., Butkova T.V., Luzgina N.G.
Protein dataset of immortalized keratinocyte HaCaT cells and normal human keratinocytes.
Data Brief 35:106871.1-106871.6(2021)

PubMed=35072517; DOI=10.1289/EHP9676; PMCID=PMC8785870
Ferragut Cardoso A.P., Banerjee M., Al-Eryani L., Sayed M., Wilkey D.W., Merchant M.L., Park J.W., States J.C.
Temporal modulation of differential alternative splicing in HaCaT human keratinocyte cell line chronically exposed to arsenic for up to 28 wk.
Environ. Health Perspect. 130:17011.1-17011.16(2022)

PubMed=35647242; DOI=10.1016/j.dib.2022.108274; PMCID=PMC9130082
Romashin D.D., Rusanov A.L., Kozhin P.M., Karagyaur M.N., Tikhonova O.V., Zgoda V.G., Luzgina N.G.
Impact of p53 knockdown on protein dataset of HaCaT cells.
Data Brief 42:108274.1-108274.8(2022)