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Cellosaurus HaCaT-hGSTP1 ARE-SV40p-Luc2 (CVCL_B6YN)

[Text version]
Cell line name HaCaT-hGSTP1 ARE-SV40p-Luc2
Accession CVCL_B6YN
Resource Identification Initiative To cite this cell line use: HaCaT-hGSTP1 ARE-SV40p-Luc2 (RRID:CVCL_B6YN)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2021113.
Population: Caucasian.
Characteristics: Expression of the luciferase reporter gene is under the control of the antioxidant response element (ARE) of GSTP1 (Patent=CN113265423B).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Derived from site: In situ; Back, skin, epidermis; UBERON=UBERON_0001068+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.843_844CC>TT); Zygosity=Heterozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0038 (HaCaT)
Sex of cell Male
Age at sampling 62Y
Category Spontaneously immortalized cell line
Publications

Patent=CN113265423B
Chen T., Yin Q.-F.
Construction and application of cell line containing luciferase reporter gene of human GSTP1 ARE.
Patent number CN113265423B, 23-Aug-2022

Cross-references
Cell line databases/resources CCRID; 4201PAT-CCTCC01845
Encyclopedic resources Wikidata; Q111733262
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number7