Cellosaurus logo
expasy logo

Cellosaurus CHO Pro-3 (CVCL_7182)

[Text version]
Cell line name CHO Pro-3
Synonyms CHO-pro3-; CHO pro3-; CHP PRO-3; Pro-3 CHO; CHO Toronto; CHO-Toronto; CHO WTB; WTB; Pro- (CHO); pro-; Pro-3
Accession CVCL_7182
Resource Identification Initiative To cite this cell line use: CHO Pro-3 (RRID:CVCL_7182)
Comments Characteristics: Defective in purine biosynthesis.
Doubling time: 14 hours (PubMed=1028172).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0213 (CHO)
Children:
CVCL_C5S2 (CHO Pro-3 MtxRI OuaR-3-6)CVCL_C5S3 (CHO Pro-3 MtxRI-2-6)CVCL_C5S4 (CHO Pro-3 MtxRI-3-3)
CVCL_C5S5 (CHO Pro-3 MtxRI-4-3)CVCL_C5S6 (CHO Pro-3 MtxRI-6-3)CVCL_C5S7 (CHO Pro-3 MtxRII OuaR-5-3)
CVCL_C5S8 (CHO Pro-3 MtxRII-5-3)CVCL_C5S9 (CHO Pro-3 MtxRII-7-5)CVCL_C5SA (CHO Pro-3 MtxRIII OuaR-3-5)
CVCL_C5SB (CHO Pro-3 MtxRIII-1-2)CVCL_C5SC (CHO Pro-3 OuaR-1-2)CVCL_7180 (CHO-DG44)
CVCL_A5KD (CHO-K1 Mev-1)CVCL_7181 (CHO-MG)CVCL_RG45 (EOT-3)
CVCL_DD06 (N211-1-8)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages https://en.wikipedia.org/wiki/Chinese_hamster_ovary_cell
Publications

PubMed=1028172; DOI=10.1007/BF01538963
Flintoff W.F., Davidson S.V., Siminovitch L.
Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells.
Somatic Cell Genet. 2:245-261(1976)

PubMed=688393; DOI=10.1016/0092-8674(78)90354-9
Gupta R.S., Chan D.Y.-H., Siminovitch L.
Evidence for functional hemizygosity at the Emtr locus in CHO cells through segregation analysis.
Cell 14:1007-1013(1978)

PubMed=730780; DOI=10.1002/jcp.1040970321
Gupta R.S., Chan D.Y.-H., Siminovitch L.
Evidence for variation in the number of functional gene copies at the AmaR locus in Chinese hamster cell lines.
J. Cell. Physiol. 97:461-467(1978)

DOI=10.3390/pr1030296
Wurm F.M.
CHO quasispecies -- implications for manufacturing processes.
Processes 1:296-311(2013)

Cross-references
Encyclopedic resources Wikidata; Q54813099
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number13