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Cellosaurus CHO Pro-3 MtxRI-2-6 (CVCL_C5S3)

[Text version]
Cell line name CHO Pro-3 MtxRI-2-6
Synonyms Pro-3 MtxRI-2-6; Pro-3 MtxRI2-6
Accession CVCL_C5S3
Resource Identification Initiative To cite this cell line use: CHO Pro-3 MtxRI-2-6 (RRID:CVCL_C5S3)
Comments Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_7182 (CHO Pro-3)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=1028172; DOI=10.1007/BF01538963
Flintoff W.F., Davidson S.V., Siminovitch L.
Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells.
Somatic Cell Genet. 2:245-261(1976)

PubMed=7003776; DOI=10.1007/BF01539153
Flintoff W.F., Weber M.
Selection of wild-type revertants from methotrexate-resistant cells containing an altered dihydrofolate reductase.
Somatic Cell Genet. 6:517-528(1980)

Cross-references
Encyclopedic resources Wikidata; Q116048745
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number5