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Cellosaurus CHO-MG (CVCL_7181)

[Text version]
Cell line name CHO-MG
Synonyms CHOMG; CHO MG; Pro-3 MG(R) 2-2
Accession CVCL_7181
Resource Identification Initiative To cite this cell line use: CHO-MG (RRID:CVCL_7181)
Comments Selected for resistance to: ChEBI; CHEBI:43996; Mitoguazone (Methylglyoxal bis-(guanylhydrazone); MGBG).
Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Caution: Four MGBG-resistant cell lines (Pro-3 MG(R) 1-23, Pro-3 MG(R) 2-2, Pro-3 MG(R) 3-1 and Pro-6 MG(R) 4-8) were created (PubMed=730773). As it is not clear which cell line has been distributed under the name CHO-MG, we have selected Pro-3 MG(R) 2-2 as it is used extensively in the original paper.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_7182 (CHO Pro-3)
Children:
CVCL_C8RP (MG-1)CVCL_C8RQ (MG-2)CVCL_C8RR (MG-3 [Hamster])
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=730773; DOI=10.1002/jcp.1040970308
Mandel J.-L., Flintoff W.F.
Isolation of mutant mammalian cells altered in polyamine transport.
J. Cell. Physiol. 97:335-343(1978)

PubMed=2766456; DOI=10.1093/carcin/10.9.1613
Dolan M.E., Norbeck L., Clyde C., Hora N.K., Erickson L.C., Pegg A.E.
Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
Carcinogenesis 10:1613-1619(1989)

PubMed=2782395; DOI=10.1152/ajpcell.1989.257.3.C545
Byers T.L., Pegg A.E.
Properties and physiological function of the polyamine transport system.
Am. J. Physiol. 257:C545-C553(1989)

Cross-references
Anatomy/cell type resources BTO; BTO:0004065
Chemistry resources ChEMBL-Cells; CHEMBL3307646
ChEMBL-Targets; CHEMBL614558
PubChem_Cell_line; CVCL_7181
Encyclopedic resources Wikidata; Q54813079
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number13