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Cellosaurus CHO Pro-3 MtxRII-5-3 (CVCL_C5S8)

[Text version]
Cell line name CHO Pro-3 MtxRII-5-3
Synonyms Pro-3 MtxRII-5-3; Pro-3 MtxRII 5-3; MtxRII 5-3
Accession CVCL_C5S8
Resource Identification Initiative To cite this cell line use: CHO Pro-3 MtxRII-5-3 (RRID:CVCL_C5S8)
Comments Doubling time: 15 hours (PubMed=1028172).
Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_7182 (CHO Pro-3)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=1028172; DOI=10.1007/BF01538963
Flintoff W.F., Davidson S.V., Siminovitch L.
Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells.
Somatic Cell Genet. 2:245-261(1976)

PubMed=1035580; DOI=10.1007/BF02835450
Flintoff W.F., Spindler S.M., Siminovitch L.
Genetic characterization of methotrexate-resistant chinese hamster ovary cells.
In Vitro 12:749-757(1976)

Cross-references
Encyclopedic resources Wikidata; Q116048750
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number5