Cellosaurus logo
expasy logo

Cellosaurus HB1.F3 (CVCL_LJ44)

[Text version]
Cell line name HB1.F3
Synonyms F3; F3-WT
Accession CVCL_LJ44
Resource Identification Initiative To cite this cell line use: HB1.F3 (RRID:CVCL_LJ44)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P01110; Avian myelocytomatosis virus MC29 v-Myc.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: v-Myc.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Fetal brain, telencephalon; UBERON=UBERON_0014371.
Cell type: Neural stem cell; CL=CL_0000047.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B7F6 (F3-effLuc)CVCL_LJ45 (HB1.F3.CD21)CVCL_LJ46 (HB1.F3.EGFRviii)
CVCL_E3V6 (HB1.F3.NeuroD)CVCL_LJ47 (HB1.F3.Ngn1)CVCL_LJ48 (HB1.F3.Ras)
Sex of cell Female
Age at sampling 14FW
Category Transformed cell line
Publications

PubMed=12167771; DOI=10.1097/00001756-200208070-00020
Cho T., Bae J.-H., Choi H.B., Kim S.S., McLarnon J.G., Suh-Kim H., Kim S.U., Min C.K.
Human neural stem cells: electrophysiological properties of voltage-gated ion channels.
NeuroReport 13:1447-1452(2002)

PubMed=15484694; DOI=10.1111/j.1440-1789.2004.00552.x
Kim S.U.
Human neural stem cells genetically modified for brain repair in neurological disorders.
Neuropathology 24:159-171(2004)

PubMed=19813087; DOI=10.1007/s10571-009-9466-3
Satoh J.-i., Obayashi S., Tabunoki H., Wakana T., Kim S.U.
Stable expression of neurogenin 1 induces LGR5, a novel stem cell marker, in an immortalized human neural stem cell line HB1.F3.
Cell. Mol. Neurobiol. 30:415-426(2010)

PubMed=21755312; DOI=10.1007/s12015-011-9280-4; PMCID=PMC4043123
Lee J.-S., Lee H.J., Moon B.-H., Song S.-H., Lee M.-O., Shim S.H., Kim H.S., Lee M.C., Kwon J.T., Fornace A.J. Jr., Kim S.U., Cha H.-J.
Generation of cancerous neural stem cells forming glial tumor by oncogenic stimulation.
Stem Cell Rev. Rep. 8:532-545(2012)

PubMed=25198726; DOI=10.1371/journal.pone.0105129; PMCID=PMC4157740
Hwang D.W., Jin Y., Lee D.H., Kim H.Y., Cho H.N., Chung H.J., Park Y., Youn H., Lee S.J., Lee H.J., Kim S.U., Wang K.-C., Lee D.S.
In vivo bioluminescence imaging for prolonged survival of transplanted human neural stem cells using 3D biocompatible scaffold in corticectomized rat model.
PLoS ONE 9:E105129-E105129(2014)

PubMed=25096191; DOI=10.1093/neuonc/nou145; PMCID=PMC4483050
Lee J.-S., Park J.-R., Kwon O.-S., Lee T.-H., Nakano I., Miyoshi H., Chun K.-H., Park M.-J., Lee H.J., Kim S.U., Cha H.-J.
SIRT1 is required for oncogenic transformation of neural stem cells and for the survival of 'cancer cells with neural stemness' in a p53-dependent manner.
Neuro-oncol. 17:95-106(2015)

PubMed=28830458; DOI=10.1186/s12943-017-0703-y; PMCID=PMC5567886
Kwon S.-J., Kwon O.-S., Kim K.-T., Go Y.-H., Yu S.-I., Lee B.-H., Miyoshi H., Oh E., Cho S.-J., Cha H.-J.
Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii.
Mol. Cancer 16:140.1-140.13(2017)

Cross-references
Anatomy/cell type resources BTO; BTO_0002893
Encyclopedic resources Wikidata; Q54881352
Gene expression databases GEO; GSM456723
GEO; GSM456725
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number9