Publications | PubMed=1196376; DOI=10.1038/258427a0 Taylor A.M.R., Harnden D.G., Arlett C.F., Harcourt S.A., Lehmann A.R., Stevens S., Bridges B.A. Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity. Nature 258:427-429(1975) PubMed=1214825; DOI=10.1016/0027-5107(75)90209-2 Arlett C.F., Harcourt S.A., Broughton B.C. The influence of caffeine on cell survival in excision-proficient and excision-deficient xeroderma pigmentosum and normal human cell strains following ultraviolet-light irradiation. Mutat. Res. 33:341-346(1975) PubMed=837385 Lehmann A.R., Kirk-Bell S., Arlett C.F., Harcourt S.A., de Weerd-Kastelein E.A., Keijzer W., Hall-Smith P. Repair of ultraviolet light damage in a variety of human fibroblast cell strains. Cancer Res. 37:904-910(1977) PubMed=7360141; DOI=10.1016/0027-5107(80)90180-3 Marshall R.R., Arlett C.F., Harcourt S.A., Broughton B.C. Increased sensitivity of cell strains from Cockayne's syndrome to sister-chromatid-exchange induction and cell killing by UV light. Mutat. Res. 69:107-112(1980) PubMed=7471106 Arlett C.F., Harcourt S.A. Survey of radiosensitivity in a variety of human cell strains. Cancer Res. 40:926-932(1980) PubMed=11219864; DOI=10.1093/carcin/1.9.745 Arlett C.F., Harcourt S.A., Lehmann A.R., Stevens S., Ferguson-Smith M.A., Morley W.N. Studies on a new case of xeroderma pigmentosum (XP3BR) from complementation group G with cellular sensitivity to ionizing radiation. Carcinogenesis 1:745-751(1980) PubMed=7067035; DOI=10.1093/carcin/3.1.33 Teo I.A., Arlett C.F. The response of a variety of human fibroblast cell strains to the lethal effects of alkylating agents. Carcinogenesis 3:33-37(1982) DOI=10.1007/978-1-4757-1117-2_12 Arlett C.F., Harcourt S.A. The mutagen sensitivity response of cells from individuals heterozygous for DNA repair deficiency genes. (In book chapter) The use of human cells for the evaluation of risk from physical and chemical agents; Castellani A. (eds.); pp.155-167; Springer; Boston; USA (1983) PubMed=6408472; DOI=10.1016/0027-5107(83)90177-X Teo I.A., Arlett C.F., Harcourt S.A., Priestley A., Broughton B.C. Multiple hypersensitivity to mutagens in a cell strain (46BR) derived from a patient with immuno-deficiencies. Mutat. Res. 107:371-386(1983) PubMed=6600729; DOI=10.1080/09553008314550171 Arlett C.F., Priestley A. Defective recovery from potentially lethal damage in some human fibroblast cell strains. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 43:157-167(1983) PubMed=2903889; DOI=10.1080/09553008814552321 Arlett C.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.V. Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes. Int. J. Radiat. Biol. 54:911-928(1988) PubMed=2973075; DOI=10.2307/3577479 Fertil B., Deschavanne P.J., Debieu D., Malaise E.-P. Correlation between PLD repair capacity and the survival curve of human fibroblasts in exponential growth phase: analysis in terms of several parameters. Radiat. Res. 116:74-88(1988) PubMed=2400879; DOI=10.1259/0007-1285-63-752-624 Plowman P.N., Bridges B.A., Arlett C.F., Hinney A., Kingston J.E. An instance of clinical radiation morbidity and cellular radiosensitivity, not associated with ataxia-telangiectasia. Br. J. Radiol. 63:624-628(1990) PubMed=1372096; DOI=10.1016/0921-8777(92)90074-d Arlett C.F., Harcourt S.A., Cole J., Green M.H.L., Anstey A.V. A comparison of the response of unstimulated and stimulated T-lymphocytes and fibroblasts from normal, xeroderma pigmentosum and trichothiodystrophy donors to the lethal action of UV-C. Mutat. Res. 273:127-135(1992) PubMed=7882314 Badie C., Iliakis G., Foray N., Alsbeih G.A., Pantellias G.E., Okayasu R., Cheong N., Russell N.S., Begg A.C., Arlett C.F., Malaise E.-P. Defective repair of DNA double-strand breaks and chromosome damage in fibroblasts from a radiosensitive leukemia patient. Cancer Res. 55:1232-1234(1995) PubMed=8609460; DOI=10.1080/095530096146075 Alsbeih G.A., Fertil B., Arlett C.F., Malaise E.-P. High split-dose recovery in hypersensitive human fibroblasts: a case of induced radioresistance? Int. J. Radiat. Biol. 69:225-239(1996) PubMed=8823375; DOI=10.1111/1523-1747.ep12584287 Moriwaki S.-i., Stefanini M., Lehmann A.R., Hoeijmakers J.H.J., Robbins J.H., Rapin I., Botta E., Tanganelli B., Vermeulen W., Broughton B.C., Kraemer K.H. DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and Cockayne syndrome resemble xeroderma pigmentosum cells. J. Invest. Dermatol. 107:647-653(1996) PubMed=10022907; DOI=10.1128/mcb.19.3.2206; PMCID=PMC84013 Cordonnier A.M., Lehmann A.R., Fuchs R.P.P. Impaired translesion synthesis in xeroderma pigmentosum variant extracts. Mol. Cell. Biol. 19:2206-2211(1999) PubMed=10987302 Girard P.-M., Foray N., Stumm M., Waugh A.P.W., Riballo E., Maser R.S., Phillips W.P., Petrini J.H.J., Arlett C.F., Jeggo P.A. Radiosensitivity in Nijmegen breakage syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects. Cancer Res. 60:4881-4888(2000) PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459 Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G. Short tandem repeat profiling provides an international reference standard for human cell lines. Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001) PubMed=12082606; DOI=10.1038/sj.onc.1205596 Girard P.-M., Riballo E., Begg A.C., Waugh A.P.W., Jeggo P.A. Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest. Oncogene 21:4191-4199(2002) PubMed=12604777; DOI=10.1073/pnas.0437964100; PMCID=PMC151363 Dai Y., Kysela B., Hanakahi L.A., Manolis K., Riballo E., Stumm M., Harville T.O., West S.C., Oettinger M.A., Jeggo P.A. Nonhomologous end joining and V(D)J recombination require an additional factor. Proc. Natl. Acad. Sci. U.S.A. 100:2462-2467(2003) PubMed=15130666; DOI=10.1016/j.exger.2004.02.002 Bridger J.M., Kill I.R. Aging of Hutchinson-Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis. Exp. Gerontol. 39:717-724(2004) PubMed=15574327; DOI=10.1016/j.molcel.2004.10.029 Riballo E., Kuhne M., Rief N., Doherty A., Smith G.C.M., Recio M.-J., Reis C., Dahm K., Fricke A., Krempler A., Parker A.R., Jackson S.P., Gennery A.R., Jeggo P.A., Lobrich M. A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol. Cell 16:715-724(2004) PubMed=16714754; DOI=10.1259/bjr/83726649 Arlett C.F., Plowman P.N., Rogers P.B., Parris C.N., Abbaszadeh F., Green M.H.L., McMillan T.J., Bush C., Foray N., Lehmann A.R. Clinical and cellular ionizing radiation sensitivity in a patient with xeroderma pigmentosum. Br. J. Radiol. 79:510-517(2006) PubMed=19179371; DOI=10.1093/nar/gkp023; PMCID=PMC2651789 Limsirichaikul S., Niimi A., Fawcett H., Lehmann A.R., Yamashita S., Ogi T. A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU). Nucleic Acids Res. 37:e31.1-e31.10(2009) |