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Cellosaurus 1BR.3.N (CVCL_2282)

[Text version]
Cell line name 1BR.3.N
Synonyms 1BR3.N; 1BR.3N; 1BR.3NEO; 1BR.3neo; 1BR3neo; 1BRneo
Accession CVCL_2282
Resource Identification Initiative To cite this cell line use: 1BR.3.N (RRID:CVCL_2282)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2279 (1BR3)
Sex of cell Male
Age at sampling 23Y
Category Transformed cell line
STR profile Source(s): ECACC=90020508; PubMed=11416159

Markers:
AmelogeninX,Y
CSF1PO9,13
D5S81812
D7S8208,10
D8S117912,14
D13S3179,12
D16S53912,14
D21S1130
FGA21,22
TH019.3
TPOX11
vWA14,15

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Publications

PubMed=2903889; DOI=10.1080/09553008814552321
Arlett C.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.V.
Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes.
Int. J. Radiat. Biol. 54:911-928(1988)

PubMed=1549511; DOI=10.1093/nar/20.5.991; PMCID=PMC312081
Jones C.J., Cleaver J.E., Wood R.D.
Repair of damaged DNA by extracts from a xeroderma pigmentosum complementation group A revertant and expression of a protein absent in its parental cell line.
Nucleic Acids Res. 20:991-995(1992)

PubMed=7519740; DOI=10.1016/0165-7992(94)90014-0
Jones C.J., Lloyd R.S., Wood R.D.
Analysis of cells harboring a putative DNA repair gene reveals a lack of evidence for a second independent xeroderma pigmentosum group A correcting gene.
Mutat. Res. 324:159-164(1994)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=12604777; DOI=10.1073/pnas.0437964100; PMCID=PMC151363
Dai Y., Kysela B., Hanakahi L.A., Manolis K., Riballo E., Stumm M., Harville T.O., West S.C., Oettinger M.A., Jeggo P.A.
Nonhomologous end joining and V(D)J recombination require an additional factor.
Proc. Natl. Acad. Sci. U.S.A. 100:2462-2467(2003)

PubMed=16714754; DOI=10.1259/bjr/83726649
Arlett C.F., Plowman P.N., Rogers P.B., Parris C.N., Abbaszadeh F., Green M.H.L., McMillan T.J., Bush C., Foray N., Lehmann A.R.
Clinical and cellular ionizing radiation sensitivity in a patient with xeroderma pigmentosum.
Br. J. Radiol. 79:510-517(2006)

Cross-references
Cell line collections (Providers) ECACC; 90020508
Cell line databases/resources CLO; CLO_0001156
CLDB; cl30
Encyclopedic resources Wikidata; Q54582781
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number16