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Cellosaurus 1BR.3.G (CVCL_2280)

[Text version]
Cell line name 1BR.3.G
Synonyms 1BR.3-G; 1BR3.G; 1BR.3GPT; 1BR.3gpt
Accession CVCL_2280
Resource Identification Initiative To cite this cell line use: 1BR.3.G (RRID:CVCL_2280)
Comments Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-gpt).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2279 (1BR3)
Children:
CVCL_2281 (1BR.3.GN)
Sex of cell Male
Age at sampling 23Y
Category Transformed cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX,Y
D8S117912,14
D18S5112,14
D21S1130
FGA21,22
TH019.3
vWA14,15

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Publications

PubMed=3002824; DOI=10.1016/0014-4827(86)90356-3
Mayne L.V., Priestley A., James M.R., Burke J.F.
Efficient immortalization and morphological transformation of human fibroblasts by transfection with SV40 DNA linked to a dominant marker.
Exp. Cell Res. 162:530-538(1986)

PubMed=2903889; DOI=10.1080/09553008814552321
Arlett C.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.V.
Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes.
Int. J. Radiat. Biol. 54:911-928(1988)

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=16714754; DOI=10.1259/bjr/83726649
Arlett C.F., Plowman P.N., Rogers P.B., Parris C.N., Abbaszadeh F., Green M.H.L., McMillan T.J., Bush C., Foray N., Lehmann A.R.
Clinical and cellular ionizing radiation sensitivity in a patient with xeroderma pigmentosum.
Br. J. Radiol. 79:510-517(2006)

Cross-references
Cell line collections (Providers) ECACC; 90020507
Cell line databases/resources CLO; CLO_0001154
CLDB; cl28
Anatomy/cell type resources BTO; BTO:0004971
Encyclopedic resources Wikidata; Q54582777
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number17