Cellosaurus MKN28 (CVCL_1416)
Cell line name | MKN28 | ||||||||||||||||||||||
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Synonyms | MKN-28; MKN 28 | ||||||||||||||||||||||
Accession | CVCL_1416 | ||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: MKN28 (RRID:CVCL_1416) | ||||||||||||||||||||||
Comments | Problematic cell line: Contaminated. Shown to be a MKN74 derivative (PubMed=20143388). Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: JFCR39 cancer cell line panel. Part of: JFCR45 cancer cell line panel. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00328. Population: Japanese. Doubling time: 28-32 hours (PubMed=3962675); 28 hours (PubMed=29435981); 30-34 hours (CelloPub=CLPUB00584). Microsatellite instability: Stable (MSS) (PubMed=23671654; Sanger). Omics: CRISPR phenotypic screen. Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from site: Metastatic; Liver; UBERON=UBERON_0002107. | ||||||||||||||||||||||
Sequence variations | |||||||||||||||||||||||
HLA typing | Source: PubMed=9023415
Source: PubMed=25960936
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Genome ancestry | Source: PubMed=30894373
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Disease | Gastric tubular adenocarcinoma (NCIt: C5473) | ||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||
Hierarchy | Parent: CVCL_2791 (MKN74) Children:
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Sex of cell | Male | ||||||||||||||||||||||
Age at sampling | 37Y | ||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||
STR profile | Source(s): Cosmic-CLP=908139; JCRB=JCRB0253; KCLB=80102; RCB=RCB1000 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||
Web pages | https://cellbank.nibiohn.go.jp/legacy/cellbank/qualitycontrol/identification/summary.htm https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx | ||||||||||||||||||||||
Publications | CLPUB00581 CLPUB00584 PubMed=758928; DOI=10.1038/bjc.1979.3; PMCID=PMC2009802 PubMed=6862145; DOI=10.20772/cancersci1959.74.2_240 PubMed=3986962; DOI=10.1093/carcin/6.4.549 PubMed=3962675; DOI=10.1111/j.1440-1827.1986.tb01461.x PubMed=1933850 PubMed=1370612; DOI=10.1016/S0006-291X(05)80133-0 DOI=10.1016/B978-0-12-333530-2.50014-9 PubMed=9023415; DOI=10.1006/cimm.1996.1062 PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D PubMed=11107048; DOI=10.1046/j.1440-1827.2000.01117.x PubMed=11314020; DOI=10.1038/sj.onc.1204160 PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x; PMCID=PMC11160020 PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234 PubMed=15900046; DOI=10.1093/jnci/dji133 PubMed=15901131; DOI=10.1016/j.prp.2005.01.002 PubMed=20143388; DOI=10.1002/ijc.25242 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=22336246; DOI=10.1016/j.bmc.2012.01.017 PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122 PubMed=23671654; DOI=10.1371/journal.pone.0063056; PMCID=PMC3646030 PubMed=25960936; DOI=10.4161/21624011.2014.954893; PMCID=PMC4355981 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=29435981; DOI=10.1002/ijc.31304 PubMed=29717028; DOI=10.1042/BSR20180277; PMCID=PMC6050193 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=30971826; DOI=10.1038/s41586-019-1103-9 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||
Cell line collections (Providers) | JCRB; JCRB0253
JCRB; NIHS0324 - Discontinued JCRB; NIHS0325 - Discontinued JCRB; FDSC0011 - Discontinued KCLB; 80102 RCB; RCB1000 - Discontinued | ||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0037142
cancercelllines; CVCL_1416 Cell_Model_Passport; SIDM00260 CGH-DB; 119-1 CGH-DB; 9021-4 Cosmic-CLP; 908139 DepMap; ACH-002161 LINCS_LDP; LCL-1922 | ||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0002381 | ||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03151847 | ||||||||||||||||||||||
CRISP screens repositories | BioGRID_ORCS_Cell_line; 944 | ||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3307602
ChEMBL-Targets; CHEMBL614353 GDSC; 908139 PharmacoDB; MKN28_937_2019 PubChem_Cell_line; CVCL_1416 | ||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54905823 | ||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0002831 | ||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 GEO; GSM562396 GEO; GSM1670112 | ||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 801338
Cosmic; 848146 Cosmic; 848371 Cosmic; 873710 Cosmic; 875905 Cosmic; 877041 Cosmic; 887249 Cosmic; 888826 Cosmic; 897534 Cosmic; 908139 Cosmic; 918496 Cosmic; 922694 Cosmic; 926113 Cosmic; 968348 Cosmic; 983726 Cosmic; 1066230 Cosmic; 1067208 Cosmic; 1090460 Cosmic; 1093298 Cosmic; 1223588 Cosmic; 1436025 Cosmic; 1460710 Cosmic; 1482081 Cosmic; 1627264 Cosmic; 1995509 Cosmic; 2036660 Cosmic; 2069778 Cosmic; 2823226 IARC_TP53; 972 IARC_TP53; 21505 Progenetix; CVCL_1416 | ||||||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 | ||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||||||
Entry history | |||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||||||||
Version number | 43 |