Cellosaurus cell line RMKN-28 (CVCL

Cross-references
Cell line name	RMKN-28
Accession	CVCL_QZ55
Resource Identification Initiative	To cite this cell line use: RMKN-28 (RRID:CVCL_QZ55)
Comments	Problematic cell line: Contaminated. Parent cell line (MKN28) has been shown to be a MKN74 derivative. Population: Japanese. Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar). Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations	Mutation; HGNC; 11998; TP53; Simple; p.Ile251Leu (c.751A>C); ClinVar=VCV000182937; Zygosity=Unspecified (PubMed=22490663).
Disease	Gastric tubular adenocarcinoma (NCIt: C5473)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1416 (MKN28)
Sex of cell	Male
Age at sampling	37Y
Category	Cancer cell line
Publications	PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122 Saiki Y., Yoshino Y., Fujimura H., Manabe T., Kudo Y., Shimada M., Mano N., Nakano T., Lee Y., Shimizu S., Oba S., Fujiwara S., Shimizu H., Chen N., Nezhad Z.K., Jin G., Fukushige S., Sunamura M., Ishida M., Motoi F., Egawa S., Unno M., Horii A. DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells. Biochem. Biophys. Res. Commun. 421:98-104(2012)
Cell line databases/resources	cancercelllines; CVCL_QZ55
Encyclopedic resources	Wikidata; Q54950673
Entry history
Entry creation	05-Mar-2018
Last entry update	05-Oct-2023
Version number	7