Cellosaurus ME-180 (CVCL_1401)
Cell line name | ME-180 | ||||||||||||||||||||||||||||||||||||
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Synonyms | Me-180; ME 180; ME180 | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_1401 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: ME-180 (RRID:CVCL_1401) | ||||||||||||||||||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). Population: Caucasian. Virology: Contains a complete HPV68 genome. Doubling time: 1.5 days (PubMed=29156801). Microsatellite instability: Stable (MSS) (Sanger). Transformant: NCBI_TaxID; 45240; Human papillomavirus type 68 (HPV68). Omics: Deep exome analysis. Omics: Deep proteome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Omics: Protein expression by reverse-phase protein arrays. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688. | ||||||||||||||||||||||||||||||||||||
Sequence variations |
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HLA typing | Source: PubMed=77569
Source: PubMed=26589293
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Genome ancestry | Source: PubMed=30894373
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Disease | Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676) Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Hierarchy | Children:
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Sex of cell | Female | ||||||||||||||||||||||||||||||||||||
Age at sampling | 66Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC=HTB-33; CCRID=3101HUMTCHu177; CLS=300196; Cosmic-CLP=687514; JCRB=JCRB0810; KCLB=30033; PubMed=22710073; PubMed=25877200; PubMed=29156801; RCB=RCB2106; TKG=TKG 0437 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-612.html | ||||||||||||||||||||||||||||||||||||
Publications | PubMed=4317734; DOI=10.1093/jnci/45.1.107 DOI=10.1007/978-1-4757-1647-4_13 PubMed=327080; DOI=10.1093/jnci/59.1.221 PubMed=833871; DOI=10.1093/jnci/58.2.209 PubMed=77569; DOI=10.1111/j.1399-0039.1978.tb01259.x PubMed=7017212; DOI=10.1093/jnci/66.6.1003 PubMed=7459858 PubMed=6220172 PubMed=6500159; DOI=10.1159/000163283 PubMed=6582512; DOI=10.1073/pnas.81.2.568; PMCID=PMC344720 PubMed=2990217; PMCID=PMC1888002 PubMed=3518877; DOI=10.3109/07357908609038260 PubMed=3371749; DOI=10.1016/0090-8258(88)90029-7 PubMed=8380785; DOI=10.1006/gyno.1993.1016 PubMed=7751322; DOI=10.1007/BF01366967 PubMed=8931502; DOI=10.3109/00016349609054706 PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D PubMed=9887230; DOI=10.1006/gyno.1998.5194 PubMed=15531914; DOI=10.1038/sj.onc.1208235 PubMed=17325662; DOI=10.1038/sj.onc.1210330 PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677 PubMed=24134916; DOI=10.1186/1755-8166-6-44; PMCID=PMC3879223 PubMed=25485619; DOI=10.1038/nbt.3080 PubMed=25877200; DOI=10.1038/nature14397 PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 PubMed=27561551; DOI=10.1038/ncomms12645; PMCID=PMC5007461 PubMed=29156801; DOI=10.18632/oncotarget.21174; PMCID=PMC5689691 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-7932 - Discontinued
ATCC; HTB-33 CLS; 300196 ICLC; HTL96027 JCRB; JCRB0810 KCLB; 30033 RCB; RCB2106 TKG; TKG 0437 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0007657
CLO; CLO_0050924 CLDB; cl3429 cancercelllines; CVCL_1401 CCRID; 3101HUMTCHu177 Cell_Model_Passport; SIDM00627 Cosmic-CLP; 687514 DepMap; ACH-001359 IGRhCellID; ME180%20GEO LINCS_LDP; LCL-1305 TOKU-E; 2410 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03471125
BioSample; SAMN03472007 BioSample; SAMN03472511 BioSample; SAMN03473047 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308114
ChEMBL-Targets; CHEMBL1075499 GDSC; 687514 PharmacoDB; ME180_910_2019 PubChem_Cell_line; CVCL_1401 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54904901 | ||||||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0006646 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2706 ArrayExpress; E-MTAB-3610 GEO; GSM113864 GEO; GSM253300 GEO; GSM595618 GEO; GSM675736 GEO; GSM685436 GEO; GSM827202 GEO; GSM1670090 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 687514
Cosmic; 760223 Cosmic; 809228 Cosmic; 846185 Cosmic; 877466 Cosmic; 928909 Cosmic; 1071909 Cosmic; 1102582 Cosmic; 1131524 Cosmic; 1175837 Cosmic; 1176609 Cosmic; 1193031 Cosmic; 1995503 Cosmic; 2301541 Cosmic; 2546868 Cosmic; 2660192 Cosmic; 2816215 IARC_TP53; 21490 Progenetix; CVCL_1401 | ||||||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD003668
PRIDE; PXD030304 | ||||||||||||||||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000610
EGA; EGAS00001000978 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||||||||||||||||||||||
Version number | 45 |