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Cellosaurus CellSensor NFkB-bla ME-180 (CVCL_KB44)

[Text version]
Cell line name CellSensor NFkB-bla ME-180
Synonyms NFkB-bla ME-180
Accession CVCL_KB44
Resource Identification Initiative To cite this cell line use: CellSensor NFkB-bla ME-180 (RRID:CVCL_KB44)
Comments Population: Caucasian.
Characteristics: Transfected with a plasmid containing a beta-lactamase reporter gene under control of the NF-kappaB response element.
Genetic integration: Method=Transfection; Gene=UniProtKB; P62593; Escherichia coli beta-lactamase bla (Note=With p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
Genetic integration: Method=Transfection; Gene=UniProtKB; P0C2P0; Aspergillus terreus blasticidin-S deaminase (Bsd).
Transformant: NCBI_TaxID; 45240; Human papillomavirus type 68 (HPV68).
Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1401 (ME-180)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
Web pages https://www.thermofisher.com/order/catalog/product/K1667
Cross-references
Cell line databases/resources cancercelllines; CVCL_KB44
Encyclopedic resources Wikidata; Q54809210
Entry history
Entry creation22-Aug-2017
Last entry update10-Sep-2024
Version number14