Cellosaurus KB (CVCL_0372)
Cell line name | KB | ||||||||||||||||||||||||||||||||||||
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Synonyms | KB (HeLa derivative); HeLa-KB; Strain KB | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_0372 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: KB (RRID:CVCL_0372) | ||||||||||||||||||||||||||||||||||||
Comments | Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=1246601; PubMed=20143388). Originally thought to originate from an epidermal carcinoma of the mouth. Part of: KuDOS 95 cell line panel. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00010. Population: African American. Doubling time: ~30 hours (DSMZ=ACC-136). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Omics: Genome sequenced (low read coverage). Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. | ||||||||||||||||||||||||||||||||||||
Disease | Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Hierarchy | Parent: CVCL_0030 (HeLa) Children:
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Sex of cell | Female | ||||||||||||||||||||||||||||||||||||
Age at sampling | 30Y6M | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC=CRL-3596; CCRID=1101HUM-PUMC000163; CLS=300446; DSMZ=ACC-136; JCRB=JCRB9027; KCLB=10017; PubMed=11416159; PubMed=17254797; TKG=TKG 0401 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/k/cell-lines-detail-494.html https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx | ||||||||||||||||||||||||||||||||||||
Publications | PubMed=13254761; DOI=10.3181/00379727-89-21811 PubMed=13322936; DOI=10.3181/00379727-91-22263 PubMed=13431913; DOI=10.3181/00379727-94-23044 PubMed=14185313; DOI=10.1126/science.146.3641.241 PubMed=4864103 PubMed=5641128; DOI=10.1038/217750a0 PubMed=5668122; DOI=10.3181/00379727-128-33119 DOI=10.1007/BF02618370 PubMed=4203458 DOI=10.1007/978-1-4757-1647-4_13 PubMed=1246601; DOI=10.1126/science.1246601 PubMed=656543; DOI=10.1016/S0006-3495(78)85487-3; PMCID=PMC1473442 PubMed=6988327; DOI=10.1007/BF02831503 PubMed=8397027 PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459 PubMed=11668190; DOI=10.1177/002215540104901105 PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001 PubMed=17325662; DOI=10.1038/sj.onc.1210330 PubMed=20143388; DOI=10.1002/ijc.25242 PubMed=23925245; DOI=10.1038/nature12064; PMCID=PMC3740412 CLPUB00484 PubMed=28455420; DOI=10.1158/0008-5472.CAN-16-2258 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | ATCC; CCL-17 - Discontinued
ATCC; CRL-3596 BCRC; 60017 - Discontinued BCRJ; 0128 CCLV; CCLV-RIE 0016 CLS; 300446 DSMZ; ACC-136 - Discontinued ECACC; 86103004 - Discontinued ECACC; 94050408 ICLC; HTL96014 - Discontinued IZSLER; BS TCL 34 JCRB; JCRB9027 KCB; KCB 94020YJ KCLB; 10017 NCBI_Iran; C152 RCB; RCB1888 - Discontinued TKG; TKG 0401 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0007074
MCCL; MCC:0000267 CLDB; cl3001 CLDB; cl3002 CLDB; cl3003 CLDB; cl3004 CLDB; cl3005 CLDB; cl3006 CCRID; 1101HUM-PUMC000163 DSMZCellDive; ACC-136 TOKU-E; 2094 | ||||||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0000665 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03151730 | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3307959
ChEMBL-Targets; CHEMBL398 PubChem_Cell_line; CVCL_0372 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q28334825 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | GEO; GSM1374595
GEO; GSM1374596 | ||||||||||||||||||||||||||||||||||||
Medical resources | MeSH; D007624 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 753567
Cosmic; 1042301 Cosmic; 1339927 Cosmic; 1969496 Cosmic; 2301581 Cosmic; 2546843 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||||||||||||||||||||||
Version number | 39 |