Cellosaurus logo
expasy logo

Cellosaurus KB-3-1 (CVCL_2088)

[Text version]
Cell line name KB-3-1
Synonyms KB 3-1; KB3-1; KB31
Accession CVCL_2088
Resource Identification Initiative To cite this cell line use: KB-3-1 (RRID:CVCL_2088)
Comments Problematic cell line: Contaminated. Parent cell line (KB) has been shown to be a HeLa derivative.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00372.
Population: African American.
Doubling time: ~40 hours (DSMZ=ACC-158).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0372 (KB)
Children:
CVCL_1D82 (KB-A1)CVCL_E3EU (KB-ChR-8)CVCL_IP04 (KB-CP.5)
CVCL_IP17 (KB-CP5)CVCL_X335 (KB-CV60)CVCL_2089 (KB-V1)
CVCL_D644 (KBH5.0)CVCL_M123 (KCP-4)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-158; PubMed=22118813

Markers:
AmelogeninX
CSF1PO9,10
D2S133817
D3S135815,18
D5S81811,12
D7S8208,12
D8S117912,13
D13S31712,13.3 (DSMZ=ACC-158)
12,14 (PubMed=22118813)
D16S5399,10
D18S5116
D19S43313,14
D21S1127,28
FGA21
Penta D8,15
Penta E7,17
TH017
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
http://www.ott.nih.gov/erma/multidrug-resistant-epidermal-carcinoma-cell-line-kb-3-1
Publications

PubMed=3856953; DOI=10.1007/BF01534700
Akiyama S.-i., Fojo A., Hanover J.A., Pastan I., Gottesman M.M.
Isolation and genetic characterization of human KB cell lines resistant to multiple drugs.
Somat. Cell Mol. Genet. 11:117-126(1985)

PubMed=2897240; DOI=10.1016/0092-8674(88)90568-5
Choi K.H., Chen C.-J., Kriegler M., Roninson I.B.
An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene.
Cell 53:519-529(1988)

PubMed=7865904
Zhang X.-P., Ritke M.K., Yalowich J.C., Slovak M.L., Ho J.P., Collins K.I., Annable T., Arceci R.J., Durr F.E., Greenberger L.M.
P-glycoprotein mediates profound resistance to bisantrene.
Oncol. Res. 6:291-301(1994)

PubMed=22118813; DOI=10.1016/j.canlet.2011.09.038
Krech T., Scheuerer E., Geffers R., Kreipe H.-H., Lehmann U., Christgen M.
ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells.
Cancer Lett. 315:153-160(2012)

PubMed=24317338; DOI=10.3892/or.2013.2896
Oiso S., Takayama Y., Nakazaki R., Matsunaga N., Motooka C., Yamamura A., Ikeda R., Nakamura K., Takeda Y., Kariyazono H.
Factors involved in the cisplatin resistance of KCP-4 human epidermoid carcinoma cells.
Oncol. Rep. 31:719-726(2014)

Cross-references
Cell line collections (Providers) DSMZ; ACC-158
Cell line databases/resources CLO; CLO_0007076
CLDB; cl3008
DSMZCellDive; ACC-158
TOKU-E; 4096
Anatomy/cell type resources BTO; BTO_0003918
Biological sample resources BioSample; SAMN03151731
Chemistry resources ChEMBL-Cells; CHEMBL3307659
ChEMBL-Targets; CHEMBL614590
PubChem_Cell_line; CVCL_2088
Encyclopedic resources Wikidata; Q54899545
Gene expression databases GEO; GSM743501
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number27