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Cellosaurus Vero E6/NPC1-KO cl.19 (CVCL_YZ66)

[Text version]
Cell line name Vero E6/NPC1-KO cl.19
Synonyms Vero E6/NPC1-KO cl. 19
Accession CVCL_YZ66
Resource Identification Initiative To cite this cell line use: Vero E6/NPC1-KO cl.19 (RRID:CVCL_YZ66)
Comments Group: Non-human primate cell line.
Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9RYM1; NPC1.
Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Chlorocebus sabaeus (Green monkey) (Simia sabaea) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0574 (Vero C1008)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=30010949; DOI=10.1093/infdis/jiy248; PMCID=PMC6927862
Kondoh T., Letko M., Munster V.J., Manzoor R., Maruyama J., Furuyama W., Miyamoto H., Shigeno A., Fujikura D., Takadate Y., Yoshida R., Igarashi M., Feldmann H., Marzi A., Takada A.
Single-nucleotide polymorphisms in human NPC1 influence filovirus entry into cells.
J. Infect. Dis. 218 Suppl. 5:S397-S402(2018)

PubMed=31940478; DOI=10.1016/j.celrep.2019.12.042; PMCID=PMC11075117
Takadate Y., Kondoh T., Igarashi M., Maruyama J., Manzoor R., Ogawa H., Kajihara M., Furuyama W., Sato M., Miyamoto H., Yoshida R., Hill T.E., Freiberg A.N., Feldmann H., Marzi A., Takada A.
Niemann-Pick C1 heterogeneity of bat cells controls filovirus tropism.
Cell Rep. 30:308-319.e5(2020)

Cross-references
Encyclopedic resources Wikidata; Q98134508
Entry history
Entry creation02-Jul-2020
Last entry update05-Oct-2023
Version number5