ID   Vero E6/NPC1-KO cl.19
AC   CVCL_YZ66
SY   Vero E6/NPC1-KO cl. 19
DR   Wikidata; Q98134508
RX   PubMed=30010949;
RX   PubMed=31940478;
CC   Group: Non-human primate cell line.
CC   Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9RYM1; NPC1.
CC   Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
OX   NCBI_TaxID=60711; ! Chlorocebus sabaeus (Green monkey)
HI   CVCL_0574 ! Vero C1008
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 02-07-20; Last updated: 05-10-23; Version: 5
//
RX   PubMed=30010949; DOI=10.1093/infdis/jiy248;
RA   Kondoh T., Letko M., Munster V.J., Manzoor R., Maruyama J.,
RA   Furuyama W., Miyamoto H., Shigeno A., Fujikura D., Takadate Y.,
RA   Yoshida R., Igarashi M., Feldmann H., Marzi A., Takada A.;
RT   "Single-nucleotide polymorphisms in human NPC1 influence filovirus
RT   entry into cells.";
RL   J. Infect. Dis. 218 Suppl. 5:S397-S402(2018).
//
RX   PubMed=31940478; DOI=10.1016/j.celrep.2019.12.042;
RA   Takadate Y., Kondoh T., Igarashi M., Maruyama J., Manzoor R.,
RA   Ogawa H., Kajihara M., Furuyama W., Sato M., Miyamoto H., Yoshida R.,
RA   Hill T.E., Freiberg A.N., Feldmann H., Marzi A., Takada A.;
RT   "Niemann-Pick C1 heterogeneity of bat cells controls filovirus
RT   tropism.";
RL   Cell Rep. 30:308-319.e5(2020).
//