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Cellosaurus HaCaT RT3 (CVCL_XK15)

[Text version]
Cell line name HaCaT RT3
Synonyms A-5RT3; RT3
Accession CVCL_XK15
Resource Identification Initiative To cite this cell line use: HaCaT RT3 (RRID:CVCL_XK15)
Comments Population: Caucasian.
Characteristics: Metastatic.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS.
Derived from site: In situ; Back, skin, epidermis; UBERON=UBERON_0001068+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.843_844CC>TT); Zygosity=Heterozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_XK16 (HaCaT A-5)
Sex of cell Male
Age at sampling 62Y
Category Spontaneously immortalized cell line
Publications

PubMed=11583982; DOI=10.1016/S0002-9440(10)62541-2; PMCID=PMC1850484
Mueller M.M., Peter W., Mappes M., Huelsen A., Steinbauer H., Boukamp P., Vaccariello M.A., Garlick J.A., Fusenig N.E.
Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor.
Am. J. Pathol. 159:1567-1579(2001)

PubMed=20097197; DOI=10.1016/j.yexcr.2010.01.020
Rasanen K., Vaheri A.
Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis.
Exp. Cell Res. 316:1739-1747(2010)

Cross-references
Encyclopedic resources Wikidata; Q93937698
Proteomic databases PRIDE; PXD013113
Entry history
Entry creation19-Dec-2019
Last entry update19-Dec-2024
Version number9