ID   HaCaT RT3
AC   CVCL_XK15
SY   A-5RT3; RT3
DR   PRIDE; PXD013113
DR   Wikidata; Q93937698
RX   PubMed=11583982;
RX   PubMed=20097197;
CC   Population: Caucasian.
CC   Characteristics: Metastatic.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.843_844CC>TT); Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS.
CC   Derived from site: In situ; Back, skin, epidermis; UBERON=UBERON_0001068+UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_XK16 ! HaCaT A-5
SX   Male
AG   62Y
CA   Spontaneously immortalized cell line
DT   Created: 19-12-19; Last updated: 19-12-24; Version: 9
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RX   PubMed=11583982; DOI=10.1016/S0002-9440(10)62541-2; PMCID=PMC1850484;
RA   Mueller M.M., Peter W., Mappes M., Huelsen A., Steinbauer H.,
RA   Boukamp P., Vaccariello M.A., Garlick J.A., Fusenig N.E.;
RT   "Tumor progression of skin carcinoma cells in vivo promoted by clonal
RT   selection, mutagenesis, and autocrine growth regulation by granulocyte
RT   colony-stimulating factor and granulocyte-macrophage
RT   colony-stimulating factor.";
RL   Am. J. Pathol. 159:1567-1579(2001).
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RX   PubMed=20097197; DOI=10.1016/j.yexcr.2010.01.020;
RA   Rasanen K., Vaheri A.;
RT   "Proliferation and motility of HaCaT keratinocyte derivatives is
RT   enhanced by fibroblast nemosis.";
RL   Exp. Cell Res. 316:1739-1747(2010).
//