Cellosaurus HCC1954-LeptoM (CVCL_XA23)
Cell line name | HCC1954-LeptoM |
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Synonyms | HCC1954 LeptoM |
Accession | CVCL_XA23 |
Resource Identification Initiative | To cite this cell line use: HCC1954-LeptoM (RRID:CVCL_XA23) |
Comments | Part of: Brain metastasis cell lines panel. Population: East Indian. Characteristics: Brain leptomeningeal space metastatic derivative of parental cell line. Established after 3 passages in nude mice from intracisternal injection, followed by one passage from intracardiac injection and obtained from mice bearing leptomeningeal metastases. Characteristics: Transfected with HSV1-TK/GFP/Fluc (TGL) and with PuroR/pac. Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Breast; UBERON=UBERON_0000310. |
Sequence variations |
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Disease | Breast ductal carcinoma (NCIt: C4017) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_VR24 (HCC1954-TGL) |
Sex of cell | Female |
Age at sampling | 61Y |
Category | Cancer cell line |
Web pages | https://apps.cnio.es/app/BrainMetastasis/CellLines |
Publications | PubMed=28283064; DOI=10.1016/j.cell.2017.02.025; PMCID=PMC5405733 |
Cross-references | |
Cell line databases/resources | cancercelllines; CVCL_XA23 |
Encyclopedic resources | Wikidata; Q93982608 |
Gene expression databases | GEO; GSM2194092
GEO; GSM2194093 GEO; GSM2194094 |
Entry history | |
Entry creation | 06-Sep-2019 |
Last entry update | 19-Dec-2024 |
Version number | 12 |