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Cellosaurus NZM048 (CVCL_S423)

[Text version]
Cell line name NZM048
Synonyms NZM48
Accession CVCL_S423
Resource Identification Initiative To cite this cell line use: NZM048 (RRID:CVCL_S423)
Comments Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (PubMed=23658559; PubMed=32567790).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
HLA typing Source: PubMed=32567790
Class I
HLA-AA*03:01,11:01
HLA-BB*45:01,45:01
HLA-CC*06:02,07:02
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D833 ! NZM042
Sex of cell Male
Age at sampling 71Y
Category Cancer cell line
STR profile Source(s): PubMed=32567790

Markers:
AmelogeninX,Y
CSF1PO9,12
D2S133817,20
D3S135816,17
D5S81812,13
D7S8208,10
D8S117914
D13S3178,11
D16S5399,11
D18S5114,16
D19S43315
D21S1129,32.2
FGA19,20
TH019,9.3
TPOX8,11
vWA16,18

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Publications

PubMed=23658559; DOI=10.3389/fgene.2013.00066
Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S., Finlay G.J., Shelling A.N., Baguley B.C.
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.
Front. Genet. 4:66.1-66.6(2013)

PubMed=23755070; DOI=10.3389/fgene.2013.00097
Kim J.E., Leung E.Y., Baguley B.C., Finlay G.J.
Heterogeneity of expression of epithelial-mesenchymal transition markers in melanocytes and melanoma cell lines.
Front. Genet. 4:97.1-97.8(2013)

PubMed=32567790; DOI=10.1111/pcmr.12908
Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R.
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma.
Pigment Cell Melanoma Res. 34:136-143(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S423
Biological sample resources BioSample; SAMN14558343
Encyclopedic resources Wikidata; Q54931582
Polymorphism and mutation databases Cosmic; 2007679
Entry history
Entry creation05-Nov-2013
Last entry update05-Oct-2023
Version number14