Cell line name |
NZM048 |
Synonyms |
NZM48 |
Accession |
CVCL_S423 |
Resource Identification Initiative |
To cite this cell line use: NZM048 (RRID:CVCL_S423) |
Comments |
Omics: Deep exome analysis. Omics: Transcriptome analysis by RNAseq. |
Sequence variations |
- Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (PubMed=23658559; PubMed=32567790).
- Mutation; HGNC; 11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=32567790).
|
HLA typing |
Source: PubMed=32567790
Class I | HLA-A | A*03:01,11:01 | HLA-B | B*45:01,45:01 | HLA-C | C*06:02,07:02 |
|
Disease |
Melanoma (NCIt: C3224) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Originate from same individual |
CVCL_D833 ! NZM042 |
Sex of cell |
Male |
Age at sampling |
71Y |
Category |
Cancer cell line |
STR profile |
Source(s): PubMed=32567790
Markers:Amelogenin | X,Y |
CSF1PO | 9,12 |
D2S1338 | 17,20 |
D3S1358 | 16,17 |
D5S818 | 12,13 |
D7S820 | 8,10 |
D8S1179 | 14 |
D13S317 | 8,11 |
D16S539 | 9,11 |
D18S51 | 14,16 |
D19S433 | 15 |
D21S11 | 29,32.2 |
FGA | 19,20 |
TH01 | 9,9.3 |
TPOX | 8,11 |
vWA | 16,18 |
Run an STR similarity search on this cell line |
Publications | PubMed=23658559; DOI=10.3389/fgene.2013.00066 Stones C.J., Kim J.E., Joseph W.R., Leung E.Y., Marshall E.S., Finlay G.J., Shelling A.N., Baguley B.C. Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors. Front. Genet. 4:66.1-66.6(2013) PubMed=23755070; DOI=10.3389/fgene.2013.00097 Kim J.E., Leung E.Y., Baguley B.C., Finlay G.J. Heterogeneity of expression of epithelial-mesenchymal transition markers in melanocytes and melanoma cell lines. Front. Genet. 4:97.1-97.8(2013) PubMed=32567790; DOI=10.1111/pcmr.12908 Tran K.B., Gimenez G., Tsai P., Kolekar S., Rodger E.J., Chatterjee A., Jabed A., Shih J.-H., Joseph W.R., Marshall E.S., Wang Q., Print C.G., Eccles M.R., Baguley B.C., Shepherd P.R. Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma. Pigment Cell Melanoma Res. 34:136-143(2021) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_S423
|
Biological sample resources |
BioSample; SAMN14558343
|
Encyclopedic resources |
Wikidata; Q54931582
|
Polymorphism and mutation databases |
Cosmic; 2007679
|
Entry history |
Entry creation | 05-Nov-2013 |
Last entry update | 05-Oct-2023 |
Version number | 14 |
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