Cellosaurus LFBK-alphaVbeta6 (CVCL_RX27)
Cell line name | LFBK-alphaVbeta6 | ||
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Synonyms | LFBK alphaVbeta6; LFBKalphaVbeta6; LF-BK alphaVbeta6; LFBK-alpha(v)beta(6); LFBK-aVb6; LFBK-AvB6; LFBKaVB6; LFBKavb6 | ||
Accession | CVCL_RX27 | ||
Resource Identification Initiative | To cite this cell line use: LFBK-alphaVbeta6 (RRID:CVCL_RX27) | ||
Comments | Group: Patented cell line. Problematic cell line: Misidentified. Parent cell line (LF-BK) was originally thought to be of bovine fetal kidney origin but originates from pig (PubMed=25617444). The derived cell line has also been shown to originate from pig (PubMed=34737324). Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00613. Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-13047. Virology: More susceptible to infection by foot-and-mouth disease virus than parent cell line. Virology: Susceptible to infection by senecavirus A (SVA) which can be used as a surrogate for studies of goot-and-mouth disease virus (PubMed=36146682). Virology: Persistently infected by bovine viral diarrhea virus (BVDV) (PubMed=34092457; PubMed=34458357; PubMed=35112907). Genetic integration: Method=Transfection/transduction; Gene=VGNC; 30323; Bovine ITGAV. Genetic integration: Method=Transfection/transduction; Gene=VGNC; 30331; Bovine ITGB6. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. | ||
Species of origin | Sus scrofa (Pig) (NCBI Taxonomy: 9823) | ||
Hierarchy | Parent: CVCL_RX26 (LF-BK) Children:
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Sex of cell | Sex unspecified | ||
Age at sampling | Age unspecified | ||
Category | Spontaneously immortalized cell line | ||
Web pages | https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx | ||
Publications | PubMed=23515553; DOI=10.1128/jcm.03370-12; PMCID=PMC3716081 Patent=US9121010 PubMed=25617444; DOI=10.1128/jcm.03220-14; PMCID=PMC4298512 PubMed=26082457; DOI=10.1177/1040638715584156 PubMed=32851014; DOI=10.3389/fvets.2020.00426; PMCID=PMC7401924 PubMed=34092457; DOI=10.1016/j.biologicals.2021.05.003 PubMed=34458357; DOI=10.3389/fvets.2021.715120; PMCID=PMC8385193 PubMed=34737324; DOI=10.1038/s41598-021-00779-5; PMCID=PMC8569163 PubMed=35112907; DOI=10.1128/mra.01167-21; PMCID=PMC8812309 PubMed=36146682; DOI=10.3390/v14091875; PMCID=PMC9503874 | ||
Cross-references | |||
Encyclopedic resources | Wikidata; Q54902456 | ||
Entry history | |||
Entry creation | 05-Mar-2018 | ||
Last entry update | 10-Sep-2024 | ||
Version number | 11 |