Cellosaurus MGPK alphaVbeta6-C5 (CVCL_A0GW)
| Cell line name | MGPK alphaVbeta6-C5 |
|---|---|
| Synonyms | MGPKalphaVbeta6-C5; MGPK aVb6-C5; MGPKaVb6-C5 |
| Accession | CVCL_A0GW |
| Resource Identification Initiative | To cite this cell line use: MGPK alphaVbeta6-C5 (RRID:CVCL_A0GW) |
| Comments | Problematic cell line: Misidentified. Grand-parent cell line (LF-BK) was originally thought to be of bovine origin but originates from pig. Virology: Combined treatment of the parent cell line with BVDV NS5A siRNA, interferon alpha and ribavirin has cured the cell line from bovine viral diarrhea virus (BVDV) infection (PubMed=34092457). Virology: Susceptible to infection by foot-and-mouth disease virus (PubMed=34092457). Genetic integration: Method=Transfection/transduction; Gene=VGNC; 30323; Bovine ITGAV. Genetic integration: Method=Transfection/transduction; Gene=VGNC; 30331; Bovine ITGB6. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. |
| Species of origin | Sus scrofa (Pig) (NCBI Taxonomy: 9823) |
| Hierarchy | Parent: CVCL_RX27 (LFBK-alphaVbeta6) |
| Sex of cell | Sex unspecified |
| Age at sampling | Age unspecified |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=34092457; DOI=10.1016/j.biologicals.2021.05.003 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q108820904 |
| Entry history | |
| Entry creation | 23-Sep-2021 |
| Last entry update | 10-Sep-2024 |
| Version number | 6 |