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Cellosaurus MGPK alphaVbeta6-C5 (CVCL_A0GW)

[Text version]
Cell line name MGPK alphaVbeta6-C5
Synonyms MGPKalphaVbeta6-C5; MGPK aVb6-C5; MGPKaVb6-C5
Accession CVCL_A0GW
Resource Identification Initiative To cite this cell line use: MGPK alphaVbeta6-C5 (RRID:CVCL_A0GW)
Comments Problematic cell line: Misidentified. Grand-parent cell line (LF-BK) was originally thought to be of bovine origin but originates from pig.
Virology: Combined treatment of the parent cell line with BVDV NS5A siRNA, interferon alpha and ribavirin has cured the cell line from bovine viral diarrhea virus (BVDV) infection (PubMed=34092457).
Virology: Susceptible to infection by foot-and-mouth disease virus (PubMed=34092457).
Transfected with: VGNC; 30323; Bovine ITGAV.
Transfected with: VGNC; 30331; Bovine ITGB6.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Hierarchy Parent: CVCL_RX27 (LFBK-alphaVbeta6)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Spontaneously immortalized cell line

PubMed=34092457; DOI=10.1016/j.biologicals.2021.05.003
LaRocco M.A., Ahmed Z., Rodriguez-Calzada M., Azzinaro P.A., Barrette R., Krug P., Rodriguez L.L., de Los Santos T., Medina G.N.
An adventitious agent-free clonal cell line that is highly susceptible to foot -and-mouth disease virus.
Biologicals 72:33-41(2021)

Encyclopedic resources Wikidata; Q108820904
Entry history
Entry creation23-Sep-2021
Last entry update05-Oct-2023
Version number5