Cellosaurus WRL-LFBK-alphavbeta6 (CVCL_C4XX)
| Cell line name | WRL-LFBK-alphavbeta6 |
|---|---|
| Synonyms | WRL-LFBK-avb6 |
| Accession | CVCL_C4XX |
| Resource Identification Initiative | To cite this cell line use: WRL-LFBK-alphavbeta6 (RRID:CVCL_C4XX) |
| Comments | Problematic cell line: Misidentified. Grand-parent cell line (LF-BK) was originally thought to be of bovine origin but originates from pig. Virology: Treatment of the parent cell line with the aromatic cationic compound DB772 has cured the cell line from bovine viral diarrhea virus (BVDV) infection (PubMed=34458357). Genetic integration: Method=Transfection/transduction; Gene=VGNC; 30323; Bovine ITGAV. Genetic integration: Method=Transfection/transduction; Gene=VGNC; 30331; Bovine ITGB6. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. |
| Species of origin | Sus scrofa (Pig) (NCBI Taxonomy: 9823) |
| Hierarchy | Parent: CVCL_RX27 (LFBK-alphaVbeta6) |
| Sex of cell | Sex unspecified |
| Age at sampling | Age unspecified |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=34458357; DOI=10.3389/fvets.2021.715120; PMCID=PMC8385193 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q116050799 |
| Entry history | |
| Entry creation | 15-Dec-2022 |
| Last entry update | 10-Sep-2024 |
| Version number | 4 |