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Cellosaurus MelHOrPLX4720_10muM (CVCL_RS67)

[Text version]
Cell line name MelHOrPLX4720_10muM
Synonyms MelHOrPLX4720(10muM)
Accession CVCL_RS67
Resource Identification Initiative To cite this cell line use: MelHOrPLX4720_10muM (RRID:CVCL_RS67)
Comments Problematic cell line: Misidentified/contaminated. Parent cell line (Mel-Ho) was reported to be isogenic with LCL-Ho (Cellosaurus=CVCL_1868) but it does not have the same STR profile.
Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:90295; PLX-4720 (PLX4720).
Derived from sampling site: Skin.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1402 (Mel Ho)
Sex of cell Female
Category Cancer cell line
Web pages https://www.wass-michaelislab.org/rccl.php
Encyclopedic resources Wikidata; Q54905182
Entry history
Entry creation05-Mar-2018
Last entry update21-Mar-2023
Version number6