ID   MelHOrPLX4720_10muM
AC   CVCL_RS67
SY   MelHOrPLX4720(10muM)
DR   cancercelllines; CVCL_RS67
DR   Wikidata; Q54905182
WW   Provider; RCCL; -; https://www.wass-michaelislab.org/rccl.php
CC   Problematic cell line: Misidentified/contaminated. Parent cell line (Mel-Ho) was reported to be isogenic with LCL-Ho (Cellosaurus=CVCL_1868) but it does not have the same STR profile.
CC   Part of: Resistant Cancer Cell Line (RCCL) collection.
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI_90295; PLX-4720 (PLX4720).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1402 ! Mel Ho
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 14-08-25; Version: 11
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