ID   RMKN-28
DR   cancercelllines; CVCL_QZ55
DR   Wikidata; Q54950673
RX   PubMed=22490663;
CC   Problematic cell line: Contaminated. Parent cell line (MKN28) has been shown to be a MKN74 derivative.
CC   Population: Japanese.
CC   Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ile251Leu (c.751A>C); ClinVar=VCV000182937; Zygosity=Unspecified (PubMed=22490663).
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
DI   NCIt; C5473; Gastric tubular adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1416 ! MKN28
SX   Male
AG   37Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 05-10-23; Version: 7
RX   PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122;
RA   Saiki Y., Yoshino Y., Fujimura H., Manabe T., Kudo Y., Shimada M.,
RA   Mano N., Nakano T., Lee Y., Shimizu S., Oba S., Fujiwara S.,
RA   Shimizu H., Chen N., Nezhad Z.K., Jin G., Fukushige S., Sunamura M.,
RA   Ishida M., Motoi F., Egawa S., Unno M., Horii A.;
RT   "DCK is frequently inactivated in acquired gemcitabine-resistant human
RT   cancer cells.";
RL   Biochem. Biophys. Res. Commun. 421:98-104(2012).