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Cellosaurus G-401 BAF47 (CVCL_QW55)

[Text version]
Cell line name G-401 BAF47
Synonyms G401 BAF47; G401_BAF47
Accession CVCL_QW55
Resource Identification Initiative To cite this cell line use: G-401 BAF47 (RRID:CVCL_QW55)
Comments Problematic cell line: Misclassified. Parent cell line (G-401) was originally thought to be a Wilms tumor cell line but is a kidney rhabdoid tumor cell line.
Population: Caucasian.
Characteristics: Transfection of SMARCB1 rescues the phenotype of the parent cell line which is homozygous for its deletion.
Transfected with: HGNC; 11103; SMARCB1.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: H3K27me3 ChIP-seq epigenome analysis.
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Disease Rhabdoid tumor of the kidney (NCIt: C8715)
Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0270 (G-401)
Sex of cell Male
Age at sampling 3M
Category Cancer cell line

PubMed=28945250; DOI=10.1038/ng.3958
Nakayama R.T., Pulice J.L., Valencia A.M., McBride M.J., McKenzie Z.M., Gillespie M.A., Ku W.L., Teng M.-X., Cui K.-R., Williams R.T., Cassel S.H., Qing H., Widmer C.J., Demetri G.D., Irizarry R.A., Zhao K.-J., Ranish J.A., Kadoch C.
SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.
Nat. Genet. 49:1613-1623(2017)

Encyclopedic resources Wikidata; Q54835348
Gene expression databases GEO; GSM2409664
GEO; GSM2409665
GEO; GSM2409666
GEO; GSM2409667
GEO; GSM2409668
GEO; GSM2409669
GEO; GSM2787353
Entry history
Entry creation15-Nov-2017
Last entry update29-Jun-2023
Version number8