Cellosaurus cell line G-401 BAF47 (CVCL

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Cellosaurus G-401 BAF47 (CVCL_QW55)

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Cross-references
Cell line name	G-401 BAF47
Synonyms	G401 BAF47; G401_BAF47
Accession	CVCL_QW55
Resource Identification Initiative	To cite this cell line use: G-401 BAF47 (RRID:CVCL_QW55)
Comments	Problematic cell line: Misclassified. Parent cell line (G-401) was originally thought to be a Wilms tumor cell line but is a kidney rhabdoid tumor cell line. Population: Caucasian. Characteristics: Transfection of SMARCB1 rescues the phenotype of the parent cell line which is homozygous for its deletion. Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11103; SMARCB1. Omics: H3K27ac ChIP-seq epigenome analysis. Omics: H3K27me3 ChIP-seq epigenome analysis. Omics: H3K4me3 ChIP-seq epigenome analysis. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Disease	Rhabdoid tumor of the kidney (NCIt: C8715) Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0270 (G-401)
Sex of cell	Male
Age at sampling	3M
Category	Cancer cell line
Publications	PubMed=28945250; DOI=10.1038/ng.3958; PMCID=PMC5803080 Nakayama R.T., Pulice J.L., Valencia A.M., McBride M.J., McKenzie Z.M., Gillespie M.A., Ku W.L., Teng M.-X., Cui K.-R., Williams R.T., Cassel S.H., Qing H., Widmer C.J., Demetri G.D., Irizarry R.A., Zhao K.-J., Ranish J.A., Kadoch C. SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters. Nat. Genet. 49:1613-1623(2017)
Encyclopedic resources	Wikidata; Q54835348
Gene expression databases	GEO; GSM2409664 GEO; GSM2409665 GEO; GSM2409666 GEO; GSM2409667 GEO; GSM2409668 GEO; GSM2409669 GEO; GSM2787353
Entry history
Entry creation	15-Nov-2017
Last entry update	10-Sep-2024
Version number	9