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Cellosaurus KAS-6/2 (CVCL_M524)

[Text version]
Cell line name KAS-6/2
Accession CVCL_M524
Resource Identification Initiative To cite this cell line use: KAS-6/2 (RRID:CVCL_M524)
Comments Characteristics: Produces IgG kappa.
Characteristics: IL6 dependent.
Cell type: B-cell; CL=CL_0000236.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9544 ! KAS-6/1
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
Web pages https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
Publications

PubMed=8656685
Westendorf J.J., Ahmann G.J., Greipp P.R., Witzig T.E., Lust J.A., Jelinek D.F.
Establishment and characterization of three myeloma cell lines that demonstrate variable cytokine responses and abilities to produce autocrine interleukin-6.
Leukemia 10:866-876(1996)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

DOI=10.1182/blood.V112.11.2732.2732
Keats J.J., Arendt B.K., Braggio E., Barrett M.T., Price-Troska T.L., Fonseca R., Bergsagel P.L., Jelinek D.F.
Comparison of multiple myeloma donor patient samples and derived cell lines identifies a confirmed hyperdiploid myeloma cell line and demonstrates remarkable genetic similarity between cell lines and patient samples.
Blood 112 Suppl. 1:2732a-2732a(2008)

Cross-references
Encyclopedic resources Wikidata; Q54899507
Entry history
Entry creation05-Nov-2013
Last entry update10-Sep-2024
Version number11