ID   KAS-6/2
AC   CVCL_M524
DR   Wikidata; Q54899507
RX   DOI=10.1182/blood.V112.11.2732.2732;
RX   PubMed=8656685;
RX   PubMed=10936422;
WW   https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
CC   Characteristics: Produces IgG kappa.
CC   Characteristics: IL6 dependent.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_9544 ! KAS-6/1
SX   Female
AG   56Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 10-09-24; Version: 11
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RX   DOI=10.1182/blood.V112.11.2732.2732;
RA   Keats J.J., Arendt B.K., Braggio E., Barrett M.T., Price-Troska T.L.,
RA   Fonseca R., Bergsagel P.L., Jelinek D.F.;
RT   "Comparison of multiple myeloma donor patient samples and derived cell
RT   lines identifies a confirmed hyperdiploid myeloma cell line and
RT   demonstrates remarkable genetic similarity between cell lines and
RT   patient samples.";
RL   Blood 112 Suppl. 1:2732a-2732a(2008).
//
RX   PubMed=8656685;
RA   Westendorf J.J., Ahmann G.J., Greipp P.R., Witzig T.E., Lust J.A.,
RA   Jelinek D.F.;
RT   "Establishment and characterization of three myeloma cell lines that
RT   demonstrate variable cytokine responses and abilities to produce
RT   autocrine interleukin-6.";
RL   Leukemia 10:866-876(1996).
//
RX   PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2;
RA   Drexler H.G., Matsuo Y.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   multiple myeloma and plasma cell leukemia.";
RL   Leuk. Res. 24:681-703(2000).
//