Cellosaurus cell line MGH-U1/OCI (CVCL

Cellosaurus MGH-U1/OCI (CVCL_LN38)

[Text version]

Cell line name

MGH-U1/OCI

Accession

CVCL_LN38

Resource Identification Initiative

To cite this cell line use: MGH-U1/OCI (RRID:CVCL_LN38)

Comments

Problematic cell line: Contaminated. Parent cell line (Ej138) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.

Sequence variations

Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).

Disease

Bladder carcinoma (NCIt: C4912)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_2443 (Ej138)
Children:

CVCL_LN39 (OCI-m/F1)

Sex of cell

Female

Age at sampling

82Y