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Cellosaurus OCI-m/F1 (CVCL_LN39)

[Text version]
Cell line name OCI-m/F1
Accession CVCL_LN39
Resource Identification Initiative To cite this cell line use: OCI-m/F1 (RRID:CVCL_LN39)
Comments Problematic cell line: Contaminated. Grand-parent cell line (Ej138) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_LN38 (MGH-U1/OCI)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line

Kovnat A., Buick R.N., Choo B., de Harven E., Kopelyan I., Trent J.M., Tannock I.F.
Malignant properties of sublines selected from a human bladder cancer cell line that contains an activated c-Ha-ras oncogene.
Cancer Res. 48:4993-5000(1988)

Cell line databases/resources cancercelllines; CVCL_LN39
Encyclopedic resources Wikidata; Q54931780
Entry history
Entry creation15-Nov-2017
Last entry update05-Oct-2023
Version number11