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Cellosaurus Jurkat 1F2-hGITR (CVCL_LH48)
Cell line name | Jurkat 1F2-hGITR |
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Synonyms | 1F2-hGITR |
Accession | CVCL_LH48 |
Resource Identification Initiative | To cite this cell line use: Jurkat 1F2-hGITR (RRID:CVCL_LH48) |
Comments | Population: Caucasian. Characteristics: One of the two IL2 alleles was inactived by CRISPR/Cas9 and a luciferase reporter gene was inserted in the loci thus expressing the luciferase gene under the control of endogenous IL2 promoter. Knockout cell: Method=CRISPR/Cas9; HGNC; 6001; IL2 (Note=1 of 2 alleles). Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11914; TNFRSF18. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: T-cell; CL=CL_0000084. |
Sequence variations |
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Disease | Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_LH47 (Jurkat 1F2) |
Sex of cell | Male |
Age at sampling | 14Y |
Category | Cancer cell line |
Publications | PubMed=28847736; DOI=10.1016/j.jim.2017.08.006 |
Cross-references | |
Cell line databases/resources | cancercelllines; CVCL_LH48 |
Encyclopedic resources | Wikidata; Q54899128 |
Entry history | |
Entry creation | 15-Nov-2017 |
Last entry update | 10-Sep-2024 |
Version number | 17 |