Cellosaurus Jurkat 1F2 (CVCL_LH47)
Cell line name | Jurkat 1F2 | |
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Synonyms | 1F2 | |
Accession | CVCL_LH47 | |
Resource Identification Initiative | To cite this cell line use: Jurkat 1F2 (RRID:CVCL_LH47) | |
Comments | Population: Caucasian. Characteristics: One of the two IL2 alleles was inactived by CRISPR/Cas9 and a luciferase reporter gene was inserted in the loci thus expressing the luciferase reporter gene under the control of endogenous IL2 promoter. Knockout cell: Method=CRISPR/Cas9; HGNC; 6001; IL2 (Note=1 of 2 alleles). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: T-cell; CL=CL_0000084. | |
Sequence variations |
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Disease | Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) | |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | |
Hierarchy | Parent: CVCL_0367 (Jurkat E6.1) Children:
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Sex of cell | Male | |
Age at sampling | 14Y | |
Category | Cancer cell line | |
Publications | PubMed=28847736; DOI=10.1016/j.jim.2017.08.006 | |
Cross-references | ||
Cell line databases/resources | cancercelllines; CVCL_LH47 | |
Encyclopedic resources | Wikidata; Q54899126 | |
Entry history | ||
Entry creation | 15-Nov-2017 | |
Last entry update | 10-Sep-2024 | |
Version number | 17 |