Cellosaurus HEK293 TL4-2B (CVCL_E3BY)
| Cell line name | HEK293 TL4-2B |
|---|---|
| Synonyms | TL4-2B |
| Accession | CVCL_E3BY |
| Resource Identification Initiative | To cite this cell line use: HEK293 TL4-2B (RRID:CVCL_E3BY) |
| Comments | Characteristics: Using pcDNA5/FRT/TO and pOG44, a linear RNA encompassing exons 2B, 3 and 4 of human SMN gene was integrated in a single site and its expression is regulated by doxycycline (PubMed=35885927). Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11117; SMN1 (Note=Exons 2B, 3 and 4). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_D585 (T-REx-293) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Publications | PubMed=35885927; DOI=10.3390/genes13071145; PMCID=PMC9323214 |
| Entry history | |
| Entry creation | 10-Sep-2024 |
| Last entry update | 10-Sep-2024 |
| Version number | 1 |