Cellosaurus UMANe002-A-2 (CVCL_D6JR)
| Cell line name | UMANe002-A-2 | |
|---|---|---|
| Accession | CVCL_D6JR | |
| Resource Identification Initiative | To cite this cell line use: UMANe002-A-2 (RRID:CVCL_D6JR) | |
| Comments | From: University of Manchester; Manchester; United Kingdom. Population: Caucasian. Characteristics: Produces a robust fluorescent signal in cardiac cells and have wide utility particularly for research on developmental biology and disease modelling (PubMed=38100908). Characteristics: Using CRISPR/Cas9 a T2A-eGFP construct was integrated at the 3'end of one allele of NKX2-5 (PubMed=38100908). Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322. | |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | |
| Hierarchy | Parent: CVCL_L201 (Man-13) Children:
| |
| Sex of cell | Male | |
| Age at sampling | Blastocyst stage | |
| Category | Embryonic stem cell | |
| Publications | PubMed=38100908; DOI=10.1016/j.scr.2023.103262 | |
| Cross-references | ||
| Cell line databases/resources | hPSCreg; UMANe002-A-2 | |
| Biological sample resources | BioSamples; SAMEA114295974 | |
| Encyclopedic resources | Wikidata; Q127384582 | |
| Entry history | ||
| Entry creation | 02-May-2024 | |
| Last entry update | 19-Dec-2024 | |
| Version number | 3 | |