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Cellosaurus HeLa S3 RUBCNL KO clone 17 (CVCL_D5AH)

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Cell line name HeLa S3 RUBCNL KO clone 17
Synonyms Pacer KO HeLa
Accession CVCL_D5AH
Resource Identification Initiative To cite this cell line use: HeLa S3 RUBCNL KO clone 17 (RRID:CVCL_D5AH)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:20420; RUBCNL.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0058 (HeLa S3)
Children:
CVCL_D5AL (HeLa S3 RUBCNL KO/HA-PRKN/HaloTag7-mGFP)CVCL_D5AM (HeLa S3 RUBCNL KO/HaloTag7-LC3)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=38728007; DOI=10.1083/jcb.202309015; PMCID=PMC11090050
Tudorica D.A., Basak B., Puerta Cordova A.S., Khuu G., Rose K.M., Lazarou M., Holzbaur E.L.F., Hurley J.H.
A RAB7A phosphoswitch coordinates Rubicon homology protein regulation of parkin-dependent mitophagy.
J. Cell Biol. 223:e202309015.1-e202309015.18(2024)

Cross-references
Encyclopedic resources Wikidata; Q127381696
Entry history
Entry creation02-May-2024
Last entry update10-Apr-2025
Version number4