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Cellosaurus HeLa S3 RUBCN KO clone 15 (CVCL_D5AG)

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Cell line name HeLa S3 RUBCN KO clone 15
Synonyms Rubicon KO HeLa
Accession CVCL_D5AG
Resource Identification Initiative To cite this cell line use: HeLa S3 RUBCN KO clone 15 (RRID:CVCL_D5AG)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; 28991; RUBCN.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0058 (HeLa S3)
Children:
CVCL_D5AJ (HeLa S3 RUBCN KO/HA-Parkin/HaloTag7-mGFP)CVCL_D5AK (HeLa S3 RUBCN KO/HaloTag7-LC3)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

DOI=10.1101/2023.08.28.555228
Tudorica D.A., Basak B., Cordova A.P., Khuu G., Rose K., Lazarou M., Holzbaur E.L.F., Hurley J.H.
A RAB7A phosphoswitch coordinates rubicon homology protein regulation of PINK1/parkin dependent mitophagy.
bioRxiv 2023:08.28.555228-08.28.555228(2023)

Cross-references
Encyclopedic resources Wikidata; Q127381693
Entry history
Entry creation02-May-2024
Last entry update10-Sep-2024
Version number2