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Cellosaurus HeLa S3 RUBCN KO/HaloTag7-LC3 (CVCL_D5AK)

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Cell line name HeLa S3 RUBCN KO/HaloTag7-LC3
Synonyms Rubicon KO S3 HeLa + HaloTag7-LC3
Accession CVCL_D5AK
Resource Identification Initiative To cite this cell line use: HeLa S3 RUBCN KO/HaloTag7-LC3 (RRID:CVCL_D5AK)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:28991; RUBCN.
Genetic integration: Method=Transfection/transduction; Gene=RGD; 621315; Map1lc3b.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P0A3G2; Rhodococcus rhodochrous dhaA (Note=Mutated = HaloTag).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D5AG (HeLa S3 RUBCN KO clone 15)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

DOI=10.1101/2023.08.28.555228
Tudorica D.A., Basak B., Cordova A.P., Khuu G., Rose K., Lazarou M., Holzbaur E.L.F., Hurley J.H.
A RAB7A phosphoswitch coordinates rubicon homology protein regulation of PINK1/parkin dependent mitophagy.
bioRxiv 2023:08.28.555228-08.28.555228(2023)

Cross-references
Encyclopedic resources Wikidata; Q127381695
Entry history
Entry creation02-May-2024
Last entry update19-Dec-2024
Version number3